Journal ArticleDOI
Preparation of 2-amino-2-C-glycosyl-acetonitriles from C-glycosyl aldehydes by Strecker reaction.
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TLDR
The direction of the nucleophilic addition appears to be governed by the configuration of the anomeric carbon with β-linked sugars, and a Felkin-Ahn selectivity can be mainly presumed.About:
This article is published in Carbohydrate Research.The article was published on 2011-12-27. It has received 4 citations till now. The article focuses on the topics: Strecker amino acid synthesis & Glycal.read more
Citations
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Nitrile-converting enzymes as a tool to improve biocatalysis in organic synthesis: recent insights and promises
TL;DR: This review focuses on the distribution and catalytic mechanism research of nitrile-converting enzymes in recent years and molecular biology aspects to improve the biocatalytic performance of microbial nitrilase and NHase.
Journal ArticleDOI
Synthetic applications of hypophosphite derivatives in reduction.
TL;DR: This review captures highlights from literature concerning phosphonic and phosphinic acid derivatives as reducing agents and evaluates their potential as alternatives, in particular to boron and aluminum hydrides.
Journal ArticleDOI
New Advances in the Synthetic Application of Enantiomeric 1-Phenylethylamine (α-PEA): Privileged Chiral Inducer and Auxiliary
TL;DR: New developments in the synthesis, resolution, and synthetic applications of chiral 1-phenylethylamine (α-PEA) reported in the last decade have been reviewed.
Journal ArticleDOI
<i>C</i>-Glycopyranosyl aldehydes: emerging chiral synthons in organic synthesis
Ashok K. Prasad,None DezhiNing +1 more
TL;DR: In this article , the authors summarized the vast array of synthetic processes that have been developed for the synthesis of C-glycopyranosyl aldehydes and diverse c-glycoconjugates derived from them by covering the literature reported from 1979 to 2023.
References
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Journal ArticleDOI
Asymmetric catalysis by chiral hydrogen-bond donors.
Mark S. Taylor,Eric N. Jacobsen +1 more
TL;DR: This review documents the structural and mechanistic features that contribute to high enantioselectivity in hydrogen-bond-mediated catalytic processes in small-molecule, synthetic catalyst systems.
Journal ArticleDOI
Highly enantioselective conjugate addition of nitromethane to chalcones using bifunctional cinchona organocatalysts.
TL;DR: Cinchona alkaloid-derived chiral bifunctional thiourea organocatalysts were synthesized and applied in the Michael addition between nitromethane and chalcones with high ee and chemical yields.
Journal ArticleDOI
Catalytic Enantioselective Strecker Reactions and Analogous Syntheses
TL;DR: This paper presents the chiral Titanium(IV) Complexes as a Catalyst for Strecker Reaction using Amines, Aldehydes, and HCN for transformation of R-Amino Nitriles into Amino Acid Amides.
Journal ArticleDOI
Enantioselective Synthesis of α-Amino Nitriles from N-Benzhydryl Imines and HCN with a Chiral Bicyclic Guanidine as Catalyst
E. J. Corey,Michael J. Grogan +1 more
TL;DR: A novel catalytic enantioselective Strecker synthesis of chiral alpha-amino nitriles and alpha-AMino acids is described and analyzed with regard to the possible mechanistic basis for stereoselectivity.
Book
Modern Amination Methods
TL;DR: In this article, the authors present a modern Allylic Amination Methods (K. Jorgensen) Eletrophilic Amination Routes from Alkenes (E.Jorgensen), Stereoselective Electrophile Amination with Sulfonyloxycarbamates and Azodicarboxylates (J.-P. Komatsu), Palladium-Catalyzed Amination of Aryl Halides and Sulfonates, J. Tietgen, et al., Syntheses of Transition Metal Nitride Complexes (C. Tom
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