Journal ArticleDOI
Prevalence of hepatitis B in the southeast of China: a population-based study with a large sample size.
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TLDR
Borderline intermediate/high endemicity was found among adults in the northern region of Zhejiang Province and the vaccination program has contributed to a reduction in infection over the last 20 years, although further efforts are required to turn the region into a ‘low-endemicity’ area.Abstract:
ObjectiveHepatitis B is a major public health problem in China. However, in the past 10 years, estimates of the prevalence of hepatitis B virus (HBV) have been sparse, with results that do not always agree. The purpose of this study was to investigate the epidemiology of HBV in adults and to provideread more
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Hepatitis B Reactivation in Patients With Previous Hepatitis B Virus Exposure Undergoing Rituximab-Containing Chemotherapy for Lymphoma: A Prospective Study
Wai-Kay Seto,Thomas S. Y. Chan,Yu-Yan Hwang,Danny Ka-Ho Wong,James Fung,Kevin Liu,Harinder Gill,Yuk-Fai Lam,Albert K. W. Lie,Ching-Lung Lai,Yok-Lam Kwong,Man-Fung Yuen +11 more
TL;DR: periodic HBV DNA monitoring was an effective strategy in preventing HBV-related complications and a high rate of HBV reactivation was observed in HBsAg-negative, anti-HBc-positive patients undergoing rituximab-containing chemotherapy, with the risk of reactivation significantly higher inAnti-HBs-negative patients.
Journal ArticleDOI
Seroepidemiology of hepatitis B virus infection in 2 million men aged 21-49 years in rural China: a population-based, cross-sectional study
TL;DR: HBV prevalence in men in rural China has changed from highly endemic into intermediate endemic in the past two decades, however, the absolute number of HBV-infected men and the susceptible population is still very large.
Journal ArticleDOI
Red blood cell distribution width is a potential prognostic index for liver disease.
Zhi-De Hu,Yi Sun,Qianqian Wang,Zhijun Han,Yuan-Lan Huang,Xiao-Fei Liu,Chun-Mei Ding,Cheng-Jin Hu,Qin Qin,Anmei Deng +9 more
TL;DR: Red blood cell distribution width is a potential prognostic index for liver disease and increased RDW was observed in liver disease patients, and was associated with worse hospital outcome among the patients with liver cirrhosis.
Journal ArticleDOI
Hepatitis B reactivation in occult viral carriers undergoing hematopoietic stem cell transplantation: A prospective study
Wai-Kay Seto,Thomas S. Y. Chan,Yu-Yan Hwang,Danny Ka-Ho Wong,James Fung,Kevin Liu,Harinder Gill,Yuk-Fai Lam,Eric H. Y. Lau,Ka Shing Cheung,Albert K. W. Lie,Ching-Lung Lai,Yok-Lam Kwong,Man-Fung Yuen +13 more
TL;DR: Hepatitis B virus reactivation in hepatitis B surface antigen (HBsAg)–negative, antibody to hepatitis B core antigen (anti‐HBc)–positive patients after allogeneic hematopoietic stem cell transplantation (HSCT) has not been prospectively studied and treatment strategies based on these parameters may prevent HBV reactivation and subsequent complications.
Journal ArticleDOI
Estimating the proportion of people with chronic hepatitis B virus infection eligible for hepatitis B antiviral treatment worldwide: a systematic review and meta-analysis.
Mingjuan Tan,Ajeet Singh Bhadoria,Fuqiang Cui,Alex Tan,Judith van Holten,Philippa Easterbrook,Nathan Ford,Qin Han,Ying Lu,Marc Bulterys,Yvan Hutin +10 more
TL;DR: The proportion of people with chronic HBV infection who were eligible for antiviral treatment worldwide, based on the WHO 2015 guidelines, was estimated, with a pooled estimate of eligibility at 19%, ranging from 12% for studies in community settings to 25% in clinic settings.
References
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TL;DR: Three elementary measures of cancer frequency are confined ourselves to: incidence, mortality and prevalence.
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Hepatitis B Virus Infection: Epidemiology and Vaccination
TL;DR: Making progress towards the elimination of HBV transmission will require sustainable vaccination programs with improved vaccination coverage, practical methods of measuring the impact of vaccination programs, and targeted vaccination efforts for communities at high risk of infection.
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Epidemiological serosurvey of hepatitis B in China--declining HBV prevalence due to hepatitis B vaccination.
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TL;DR: China has already reached the national goal of reducing HBsAg prevalence to less than 1% among children under 5 years and has prevented an estimated 16-20 million HBV carriers through hepatitis B vaccination of infants and immunization program should be further strengthened to reach those remaining at highest risk.
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TL;DR: China is now the only country in Asia where HBV endemicity is high, and future vaccination programmes must take into account the mode of transmission of HBV, the healthcare infrastructure to deliver vaccination, and the socioeconomic and political factors in each individual country to determine the most cost-effective way of infection control.
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