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Journal ArticleDOI

Proceedings of the International Consensus on Periprosthetic Joint Infection

TLDR
This paper summaries the instigation, conduct and findings of a recent International Consensus Meeting on Surgical Site and Periprosthetic Joint Infection.
Abstract
Louis Pasteur once said that: “Fortune favours the prepared mind.” As one of the great scientists who contributed to the fight against infection, he emphasised the importance of being prepared at all times to recognise infection and deal with it. Despite the many scientific discoveries and technological advances, such as the advent of antibiotics and the use of sterile techniques, infection continues to be a problem that haunts orthopaedic surgeons and inflicts suffering on patients. The medical community has implemented many practices with the intention of preventing infection and treating it effectively when it occurs. Although high-level evidence may support some of these practices, many are based on little to no scientific foundation. Thus, around the world, there is great variation in practices for the prevention and management of periprosthetic joint infection. This paper summaries the instigation, conduct and findings of a recent International Consensus Meeting on Surgical Site and Periprosthetic Joint Infection. Cite this article: Bone Joint J 2013;95-B:1450–2.

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Journal ArticleDOI

The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria.

TL;DR: This study offers an evidence-based definition for diagnosing hip and knee PJI, which has shown excellent performance on formal external validation and compared to the established MSIS and the prior International Consensus Meeting definitions.
Journal ArticleDOI

ESCMID∗ guideline for the diagnosis and treatment of biofilm infections 2014

TL;DR: The clinical and laboratory parameters for diagnosing biofilm infections are outlined based on the patient's history, signs and symptoms, microscopic findings, culture-based or culture-independent diagnostic techniques and specific immune responses to identify microorganisms known to causeBiofilm infections.
Journal ArticleDOI

Periprosthetic joint infection

TL;DR: This Review assesses risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection, and indicates for surgical management have been refined.
Journal ArticleDOI

The role of microbial biofilms in prosthetic joint infections

TL;DR: The pertinent issues surrounding PJI and the challenges posed by biofilms regarding diagnosis and treatment are discussed and novel strategies of prevention and treatment of biofilm-related PJI are discussed.
Journal ArticleDOI

Biofilms in periprosthetic orthopedic infections.

TL;DR: Prevention of infection through novel coatings for prostheses and the local delivery of high concentrations of antibiotics by absorbable carriers has shown promise in laboratory and animal studies and future diagnostic and treatment options are discussed.
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