Journal ArticleDOI
Proceedings of the International Consensus on Periprosthetic Joint Infection
TLDR
This paper summaries the instigation, conduct and findings of a recent International Consensus Meeting on Surgical Site and Periprosthetic Joint Infection.Abstract:
Louis Pasteur once said that: “Fortune favours
the prepared mind.” As one of the great scientists who contributed
to the fight against infection, he emphasised the importance of
being prepared at all times to recognise infection and deal with
it. Despite the many scientific discoveries and technological advances,
such as the advent of antibiotics and the use of sterile techniques,
infection continues to be a problem that haunts orthopaedic surgeons
and inflicts suffering on patients. The medical community has implemented many practices with the
intention of preventing infection and treating it effectively when
it occurs. Although high-level evidence may support some of these
practices, many are based on little to no scientific foundation.
Thus, around the world, there is great variation in practices for
the prevention and management of periprosthetic joint infection. This paper summaries the instigation, conduct and findings of
a recent International Consensus Meeting on Surgical Site and Periprosthetic
Joint Infection. Cite this article: Bone Joint J 2013;95-B:1450–2.read more
Citations
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Journal ArticleDOI
The 2018 Definition of Periprosthetic Hip and Knee Infection: An Evidence-Based and Validated Criteria.
Javad Parvizi,Timothy L. Tan,Karan Goswami,Carlos A. Higuera,Craig J. Della Valle,Antonia F. Chen,Noam Shohat +6 more
TL;DR: This study offers an evidence-based definition for diagnosing hip and knee PJI, which has shown excellent performance on formal external validation and compared to the established MSIS and the prior International Consensus Meeting definitions.
Journal ArticleDOI
ESCMID∗ guideline for the diagnosis and treatment of biofilm infections 2014
Niels Høiby,Thomas Bjarnsholt,Claus Moser,Gianluigi Li Bassi,Tom Coenye,Gianfranco Donelli,Luanne Hall-Stoodley,Veronika Holá,Christine Imbert,Klaus Kirketerp-Møller,David Lebeaux,Antonio Oliver,Andrew J. Ullmann,Craig Williams +13 more
TL;DR: The clinical and laboratory parameters for diagnosing biofilm infections are outlined based on the patient's history, signs and symptoms, microscopic findings, culture-based or culture-independent diagnostic techniques and specific immune responses to identify microorganisms known to causeBiofilm infections.
Journal ArticleDOI
Periprosthetic joint infection
TL;DR: This Review assesses risk factors, preventive measures, diagnoses, clinical features, and treatment options for prosthetic joint infection, and indicates for surgical management have been refined.
Journal ArticleDOI
The role of microbial biofilms in prosthetic joint infections
TL;DR: The pertinent issues surrounding PJI and the challenges posed by biofilms regarding diagnosis and treatment are discussed and novel strategies of prevention and treatment of biofilm-related PJI are discussed.
Journal ArticleDOI
Biofilms in periprosthetic orthopedic infections.
Stephen J. McConoughey,Rob Howlin,Jeff F Granger,M. M. Manring,Jason H. Calhoun,Mark E. Shirtliff,Sandeep Kathju,Paul Stoodley,Paul Stoodley +8 more
TL;DR: Prevention of infection through novel coatings for prostheses and the local delivery of high concentrations of antibiotics by absorbable carriers has shown promise in laboratory and animal studies and future diagnostic and treatment options are discussed.