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Open AccessJournal ArticleDOI

Diagnosis and Management of Prosthetic Joint Infection: Clinical Practice Guidelines by the Infectious Diseases Society of America

TLDR
These guidelines include evidence-based and opinion-based recommendations for the diagnosis and management of patients with PJI treated with debridement and retention of the prosthesis, resection arthroplasty with or without subsequent staged reimplantation.
Abstract
These guidelines are intended for use by infectious disease specialists, orthopedists, and other healthcare professionals who care for patients with prosthetic joint infection (PJI). They include evidence-based and opinion-based recommendations for the diagnosis and management of patients with PJI treated with debridement and retention of the prosthesis, resection arthroplasty with or without subsequent staged reimplantation, 1-stage reimplantation, and amputation.

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Journal ArticleDOI

Staphylococcus aureus Infections: Epidemiology, Pathophysiology, Clinical Manifestations, and Management

TL;DR: This review comprehensively covers the epidemiology, pathophysiology, clinical manifestations, and management of S. aureus as a leading cause of bacteremia and infective endocarditis as well as osteoarticular, skin and soft tissue, pleuropulmonary, and device-related infections.
Journal ArticleDOI

Prosthetic Joint Infection

TL;DR: The recently proposed consensus definitions of PJI and approaches to accurate diagnosis are reviewed in detail and an overview of the treatment and prevention of this challenging condition is provided.
Journal ArticleDOI

Implant infections: adhesion, biofilm formation and immune evasion

TL;DR: The fundamental pathogenic mechanisms underlying implant infections are explored, highlighting orthopaedic implants and Staphylococcus aureus as a prime example, and innovative targets for preventive and therapeutic strategies are discussed.
Journal ArticleDOI

ESCMID∗ guideline for the diagnosis and treatment of biofilm infections 2014

TL;DR: The clinical and laboratory parameters for diagnosing biofilm infections are outlined based on the patient's history, signs and symptoms, microscopic findings, culture-based or culture-independent diagnostic techniques and specific immune responses to identify microorganisms known to causeBiofilm infections.
References
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Journal ArticleDOI

Projections of primary and revision hip and knee arthroplasty in the United States from 2005 to 2030.

TL;DR: These large projected increases in demand for total hip and knee arthroplasties provide a quantitative basis for future policy decisions related to the numbers of orthopaedic surgeons needed to perform these procedures and the deployment of appropriate resources to serve this need.
Journal ArticleDOI

Prosthetic-Joint Infections

TL;DR: This review offers guidance in establishing the diagnosis correctly and an algorithm summarizing the appropriate medical and surgical options for prosthetic joints infections.
Journal ArticleDOI

Treatment of infections associated with surgical implants.

TL;DR: This review summarizes the diagnostic challenges and explains the approaches to managing infections that are associated with various devices, including prosthetic heart valves, vascular grafts, pacemakers and defibrillators, and joint prostheses.
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