Prognosis of diabetics with diabetes onset before the age of thirty-one. I. Survival, causes of death, and complications
Reads0
Chats0
TLDR
Clinical manifestations of late diabetic complications were considerably less common in patients who were still alive after more than forty years of diabetes than in Patients who died before their fortieth year of diabetes.Abstract:
In 307 patients with diabetes mellitus, developed prior to 1933 and before age 31 it was demonstrated that: (1) frequent contact with a specialized diabetes clinic from an early stage of the disease; (2) a good quality of “metabolic control”; (3) a low insulin dose; (4) a body weight of 10% less than ideal; and (5) a mean blood pressure below 100 mm Hg, all had significantly beneficial effects upon the survival. It was also found that patients domiciled in Copenhagen had a significantly better prognosis than patients domiciled outside Copenhagen. Frequent contact with a diabetes centre was accompanied by an appreciable decrease in disabling late diabetic complications.read more
Citations
More filters
Journal ArticleDOI
The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus.
Diabetes Control,David M. Nathan,Saul M. Genuth,John M. Lachin,Patricia A. Cleary,O Crofford,Matthew M. Davis,Larry Rand,Carolyn Siebert +8 more
TL;DR: Intensive therapy effectively delays the onset and slows the progression of diabetic retinopathy, nephropathy, and neuropathy in patients with IDDM.
Journal ArticleDOI
Guidelines on diabetes, pre-diabetes, and cardiovascular diseases: executive summary. The Task Force on Diabetes and Cardiovascular Diseases of the European Society of Cardiology (ESC) and of the European Association for the Study of Diabetes (EASD).
Lars Rydén,Eberhard Standl,Malgorzata Bartnik,Greet Van den Berghe,John Betteridge,Menko-Jan de Boer,Francesco Cosentino,Bengt Jönsson,Markku Laakso,Klas Malmberg,Silvia G. Priori,Jan Östergren,Jaakko Tuomilehto,Inga Thrainsdottir,Ilse Vanhorebeek,Marco Stramba-Badiale,Peter Lindgren,Qing Qiao,Silvia G. Priori,Jean-Jacques Blanc,Andrzej Budaj,John Camm,Veronica Dean,Jaap W. Deckers,Kenneth Dickstein,John Lekakis,Keith McGregor,Marco Metra,João Morais,Ady Osterspey,Juan Tamargo,José Luis Zamorano,J.W. Deckers,Michel E. Bertrand,Bernard Charbonnel,Erland Erdmann,Ele Ferrannini,Allan Flyvbjerg,Helmut Gohlke,Jose Ramon Gonzalez Juanatey,Ian D. Graham,Pedro Filipe Monteiro,Klaus G. Parhofer,Kalevi Pyörälä,Itamar Raz,Guntram Schernthaner,Massimo Volpe,David Wood +47 more
TL;DR: Guidelines and Expert Consensus documents aim to present management and recommendations based on all of the relevant evidence on a particular subject in order to help physicians to select the best possible management strategies for the individual patient, suffering from a specific condition, taking into account not only the impact on outcome, but also the risk benefit ratio of a particular diagnostic or therapeutic procedure.
Journal ArticleDOI
Microalbuminuria as a predictor of clinical nephropathy in insulin-dependent diabetes mellitus
TL;DR: Elevated levels of microalbuminuria strongly predict the development of clinical diabetic nephropathy, and these levels of AER are potentially reversible, and their detection and treatment may prevent diabetic renal disease.
Journal ArticleDOI
The Diabetes Control and Complications Trial/Epidemiology of Diabetes Interventions and Complications Study at 30 Years: Overview
TL;DR: DCCT/EDIC has demonstrated the effectiveness of intensive therapy in reducing the long-term complications of T1DM and improving the prospects for a healthy life span and the durability of the DCCT effects on the more-advanced stages of diabetes complications including cardiovascular disease.
Journal ArticleDOI
Long-term complications of diabetes mellitus
TL;DR: Retinopathy is so characteristic of diabetes that its presence has been incorporated into the nosologic definition of NIDDM, while lower levels of hyperglycemia that are of sufficient magnitude to be associated with retinopathy are classified as NID DM.
References
More filters
Book ChapterDOI
Nonparametric Estimation from Incomplete Observations
Edward L. Kaplan,Paul Meier +1 more
TL;DR: In this article, the product-limit (PL) estimator was proposed to estimate the proportion of items in the population whose lifetimes would exceed t (in the absence of such losses), without making any assumption about the form of the function P(t).
Journal ArticleDOI
A generalized Wilcoxon test for comparing arbitrarily singly-censored samples
TL;DR: Some comparisons are made for five cases of varying degrees of censoring and tying between probabilities from the exact test and those from the proposed test and these suggest the test is appropriate under certain conditions when the sample size is five in each group.
Journal ArticleDOI
Nonparametric Inference for a Family of Counting Processes
TL;DR: In this article, the authors give an application of the recently developed martingale-based approach to the study of multivariate counting processes via $\mathbf{N}$ via ''mathbf{\Lambda''.
Journal ArticleDOI
HL-A antigens and diabetes mellitus.
J Nerup,P. Platz,O. Ortved Andersen,M. Christy,J. Lyngsoe,J E Poulsen,Lars P. Ryder,Lillian Staub Nielsen,Mogens Thomsen,Arne Svejgaard +9 more
TL;DR: The increase of HL-A8 in insulin-dependent diabetes, Graves' disease, and idiopathic Addison's disease is suggestive of a common pathogenesis of these endocrine autoimmune conditions.
Journal ArticleDOI
Factors associated with long-term survival of diabetics.
Sidney Pell,C. Anthony D'Alonzo +1 more
TL;DR: The mortality of diabetics with mild diabetes and those without complicating diseases was also substantially greater than that of the nondiabetics, and the mortality of those with mild Diabetes and those Without Complicating Diseases was substantially greater.