Journal ArticleDOI
Properties, function and origin of the alveolar lining layer.
Reads0
Chats0
TLDR
Equally stable foam is found in the bronchi of an animal the respiratory movements of which have been paralysed and into the trachea of which a mixture of oxygen and ammonia gas has been insufflated for one or two hours.Abstract:
IN acute lung œdema in the rabbit, fluid a ad foam are found in the trachea. This foam has an altogether peculiar property, in that it is unaffected by silicone anti-foams; these rapidly destroy the foams produced by shaking œdema fluid or blood serum with air. Equally stable foam is found in the bronchi of an animal the respiratory movements of which have been paralysed and into the trachea of which a mixture of oxygen and ammonia gas has been insufflated for one or two hours; similar foams are obtained from healthy lung by cutting and squeezing under water, or after introduction of saline into the trachea. The stability of such foams is due to an insoluble surface layer on the bubbles; this layer can be attacked by pancreatin or by trypsin.read more
Citations
More filters
Journal ArticleDOI
Respiration--a critical phenomenon? Lipid phase transitions in the lung alveolar surfactant.
Journal ArticleDOI
Pulmonary surfactant protein C containing lipid films at teh air-water interface as a model for the surface of lung alveoli
TL;DR: It is concluded that pure SP-C films rearrange reversibly into multilayers of homogenous thickness as well as mixed DPPG/SP-C monolayers with less than 5 mol% protein collapse in a controlled and reversible way.
Journal ArticleDOI
Lung surfactant: How it does and does not work
TL;DR: A protein-free formulation of an artificial lung-expanding compound (ALEC) consisting of a 7:3 mole/mole mixture of dipalmitoylphosphatidylcholine and phosph atidylglycerol seems to function as a reasonably good substitute for natural LS in very premature babies.
Journal ArticleDOI
Characterization and modelling of Langmuir interfaces with finite elasticity
TL;DR: The possibility to now independently measure the compressional properties of different strains and the development of an appropriate finite strain constitutive model for elastic interfaces make it possible to interrogate the underlying constitutive behaviour.
Journal ArticleDOI
Arbitrary Lagrangian-Eulerian finite-element method for computation of two-phase flows with soluble surfactants
Sashikumaar Ganesan,Lutz Tobiska +1 more
TL;DR: A finite-element scheme based on a coupled arbitrary Lagrangian-Eulerian andlagrangian approach is developed for the computation of interface flows with soluble surfactants and shows excellent conservation of fluid mass and of the total mass of the surfactant.
References
More filters