Open Access
Protection from rabies by a vaccinia virus recombinant containing the rabies virus glycoprotein gene. 1984.
Tadeusz J. Wiktor,R I Macfarlan,K J Reagan,Bernhard Dietzschold,P J Curtis,William H. Wunner,Marie-Paule Kieny,Richard Lathe,J P Lecocq,M Mackett +9 more
- Vol. 24, pp 508-512
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The article was published on 1992-01-01 and is currently open access. It has received 6 citations till now. The article focuses on the topics: Rabies virus & Duck embryo vaccine.read more
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Efficacy of (S)-1-(3-hydroxy-2-phosphonylmethoxypropyl)cytosine for the treatment of lethal vaccinia virus infections in severe combined immune deficiency (SCID) mice
Johan Neyts,Erik De Clercq +1 more
TL;DR: The VV/SCID mouse model employed here may be useful for determining whether (attenuated) recombinant VV (carrying HIV genes) may have detrimental effects in the immunodeficient host and HPMPC may be considered as a drug candidate for the treatment and prophylaxis of such complications.
Journal ArticleDOI
Human pregnancy-specific glycoprotein 1a (PSG1a) induces alternative activation in human and mouse monocytes and suppresses the accessory cell-dependent T cell proliferation.
Claudia Cristina Motran,Fernando López Diaz,Adriana Gruppi,Daniela A Slavin,Bruno Chatton,José Luis Bocco +5 more
TL;DR: The results suggest that PSG1a function contributes to the immunomodulation during pregnancy, having opposite effects on maternal innate and adaptative systems.
Journal ArticleDOI
Resistance of mice vaccinated with rabies virus internal structural proteins to lethal infection.
Y. Takita-Sonoda,H. Fujii,K Mifune,Y. Ito,M. Hiraga,Akira Nishizono,Kazuaki Mannen,Nobuyuki Minamoto +7 more
TL;DR: The authors' observations suggest that a considerable part of the protection achieved by the vaccination with rVac-N can be ascribed to the intact anti-N antibodies recognizing an epitope located on amino acids 1–224 of the protein.
Journal ArticleDOI
Isolation and characterization of human neutralizing antibodies to rabies virus derived from a recombinant immune antibody library.
Mehdi Houimel,Koussay Dellagi +1 more
TL;DR: A human immune Fab library was constructed using RNAs from peripheral blood lymphocytes obtained from rabies virus hyperimmune volunteers on phagemid vector, and the Fab fragments showed dose-dependent neutralization properties for the challenge virus standard (CVS-11).
Journal ArticleDOI
Why do poxviruses still matter
TL;DR: Poxviruses comprise many members that infect both vertebrate and invertebrate animals, including humans as discussed by the authors, and remain significant public health concerns and serious endemic diseases, despite the eradication of the historically notorious smallpox.