Journal ArticleDOI
Psychological and social sequelae of cannabis and other illicit drug use by young people: a systematic review of longitudinal, general population studies
John Macleod,R Oakes,Alex Copello,Ilana Crome,Matthias Egger,Matthias Egger,Mathew Hickman,Thomas Oppenkowski,Helen Stokes-Lampard,George Davey Smith +9 more
TLDR
Available evidence does not strongly support an important causal relation between cannabis use by young people and psychosocial harm, but cannot exclude the possibility that such a relation exists, and the lack of evidence of robust causal relations prevents the attribution of public health detriments to illicit drug use.About:
This article is published in The Lancet.The article was published on 2004-05-15. It has received 598 citations till now. The article focuses on the topics: Substance abuse & Recreational drug use.read more
Citations
More filters
Journal ArticleDOI
Adverse Health Effects of Marijuana Use
TL;DR: As marijuana use becomes legal in some states, the dominant public opinion is that marijuana is a harmless source of mood alteration, but enough information is available to cause concern.
Journal ArticleDOI
Cannabis use and risk of psychotic or affective mental health outcomes: a systematic review
Theresa Hm Moore,Stanley Zammit,Stanley Zammit,Anne Lingford-Hughes,Thomas R. E. Barnes,Peter B. Jones,Margaret Burke,Glyn Lewis +7 more
TL;DR: There is now sufficient evidence to warn young people that using cannabis could increase their risk of developing a psychotic illness later in life, although evidence for affective outcomes is less strong.
Journal ArticleDOI
The environment and schizophrenia
TL;DR: Although heritability is often emphasized, onset is associated with environmental factors such as early life adversity, growing up in an urban environment, minority group position and cannabis use, suggesting that exposure may have an impact on the developing ‘social’ brain during sensitive periods.
Journal ArticleDOI
Extent of illicit drug use and dependence, and their contribution to the global burden of disease.
Louisa Degenhardt,Wayne Hall +1 more
TL;DR: The regional and global distribution of use and estimated health burden from illicit drugs is outlined, and the health-related harms of cannabis use differ from those of amphetamine, cocaine, and opioid use, in that cannabis contributes little to mortality.
Journal ArticleDOI
Adverse health effects of non-medical cannabis use
Wayne Hall,Louisa Degenhardt +1 more
TL;DR: The most probable adverse effects include a dependence syndrome, increased risk of motor vehicle crashes, impaired respiratory function, cardiovascular disease, and adverse effects of regular use on adolescent psychosocial development and mental health.
References
More filters
Journal ArticleDOI
The environment and disease: association or causation?
TL;DR: The criteria outlined in "The Environment and Disease: Association or Causation?" help identify the causes of many diseases, including cancers of the reproductive system.
Journal Article
The environment and disease: association or causation?
TL;DR: This paper contrasts Bradford Hill’s approach with a currently fashionable framework for reasoning about statistical associations – the Common Task Framework – and suggests why following Bradford Hill, 50+ years on, is still extraordinarily reasonable.
Journal ArticleDOI
Protecting adolescents from harm: Findings from the National Longitudinal Study on Adolescent Health.
Michael D. Resnick,Peter Shawn Bearman,Robert Wm. Blum,Karl E. Bauman,Kathleen Mullan Harris,Jo Ann Jones,Joyce W. Tabor,Trisha Beuhring,Renee E. Sieving,Marcia L. Shew,Marjorie Ireland,Linda H. Bearinger,J. Richard Udry +12 more
TL;DR: Family and school contexts as well as individual characteristics are associated with health and risky behaviors in adolescents, and the results should assist health and social service providers, educators, and others in taking the first steps to diminish risk factors and enhance protective factors for young people.
Journal ArticleDOI
‘Mendelian randomization’: can genetic epidemiology contribute to understanding environmental determinants of disease?
George Davey Smith,Shah Ebrahim +1 more
TL;DR: Mendelian randomization provides new opportunities to test causality and demonstrates how investment in the human genome project may contribute to understanding and preventing the adverse effects on human health of modifiable exposures.
Journal ArticleDOI
The hazards of scoring the quality of clinical trials for meta-analysis.
TL;DR: The data indicate that the use of summary scores to identify trials of high quality is problematic, and relevant methodological aspects should be assessed individually and their influence on effect sizes explored.