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Journal ArticleDOI

Pulsatile crossflow improves microfiltration fractionation of cells and proteins

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TLDR
P pulsatile crossflow microfiltration has the highest effect, when it is applied at high transmembrane pressure, high pulsation amplitude, and a frequency above 0.2 Hz, which has a strong beneficial effect on fractionation efficiency.
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This article is published in Journal of Membrane Science.The article was published on 2021-07-01. It has received 16 citations till now. The article focuses on the topics: Cross-flow filtration & Microfiltration.

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Citations
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Journal ArticleDOI

Characterizing membrane fouling formation during ultrafiltration of high-salinity organic wastewater

TL;DR: In this paper , the authors investigated the effects of high salinity especially high-concentration Na+, Ca2+ and Al3+ on UF fouling characteristics, where 2 M Na+ and 0.5-1.0 M Ca 2+ or Al 3+ were applied according to the general composition of high-salinity wastewater.
Journal ArticleDOI

Characterizing membrane fouling formation during ultrafiltration of high-salinity organic wastewater.

TL;DR: In this paper, the authors investigated the effects of high salinity especially high-concentration Na+, Ca2+ and Al3+ on UF fouling characteristics, where 2.5 m Na+ and 0.0 m Al3 + were applied according to the general composition of high-salinity wastewater.
Journal ArticleDOI

A review of membrane fouling by proteins in ultrafiltration and microfiltration

TL;DR: In this paper , the authors present a comprehensive state-of-the-art understanding on protein fouling of membranes, along with effects of operating conditions and properties of proteins and membranes.
Journal ArticleDOI

On the effect of flow reversal during crossflow microfiltration of a cell and protein mixture

TL;DR: It is concluded that flow reversal plays a part in fouling mitigation, but a greater part of the anti-fouling effect of alternating crossflow, however, is caused by the transmembrane pressure fluctuations.
Journal ArticleDOI

Application of a Pulsed Crossflow to improve Chemical Cleaning Efficiency in Hollow Fibre Membranes following Skim Milk Microfiltration

TL;DR: In this paper , the authors examined the effects of pulsed crossflow on protein fouled polymeric microfiltration membranes, and found that pulsed flow poses a more efficient way to enhance mechanical cleaning power than by increasing the flow velocity.
References
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Journal ArticleDOI

Bioprocess membrane technology

TL;DR: An overview of recent developments in membrane technology is provided, focusing on the special characteristics of the membrane systems that are now used for the commercial production and purification of recombinant protein products.
Journal ArticleDOI

Membrane-based techniques for the separation and purification of proteins: an overview.

TL;DR: This manuscript provides an overview of recent developments and published literature in membrane technology, focusing on special characteristics of the membranes and membrane-based processes that are now used for the production and purification of proteins.
Book

The Rheology Handbook

Journal ArticleDOI

Particle deposition and layer formation at the crossflow microfiltration

TL;DR: In this article, a microscopic model of the layer formation and the cake growth at the crossflow microfiltration was introduced, which considers the hydrodynamic, adhesive and friction forces acting on a single particle during the filtration process.
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