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Journal ArticleDOI

Quality of life in adult survivors of lung, colon and prostate cancer

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TLDR
It is concluded that patients who survive cancer do not return to a state of normal health and greater efforts need to be made early in diagnosis and treatment to understand rehabilitation problems and target interventions in the hope of reducing later sequelae.
Abstract
In a cross-sectional study design, a disease free sample of 57 lung, 117 colon, and 104 prostate cancer survivors who represented short, intermediate and long-term survivors completed a detailed assessment of quality of life (QOL) and rehabilitation needs using the CAncer Rehabilitation Evaluation System (CARES). Demographic and medical data, social support, and a global QOL rating were also assessed. Lung cancer patients showed no differences in QOL with respect to their period of survival. QOL improved for survivors of colon cancer as they lived for longer periods, but declined with time for survivors of prostate cancer. The best predictor of QOL for all groups was KPS, although other variables such as type of hospital, gender, and work status were predictive for survivors of colon cancer. For survivors of prostate cancer comorbidity with other medical illnesses, time since diagnosis and comorbidity due to psychiatric difficulties were predictive of QOL. All groups had significant rehabilitation problems in the domains of physical, psychosocial, sexual, medical interaction, and marital relationships. Lung cancer survivors had more problems than the other cancer survivors. We conclude that patients who survive cancer do not return to a state of normal health. They demonstrate a variety of difficulties with which they must cope as they continue to survive. Greater efforts need to be made early in diagnosis and treatment to understand rehabilitation problems and target interventions in the hope of reducing later sequelae.

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Journal ArticleDOI

Guideline for the Management of Clinically Localized Prostate Cancer: 2007 Update

TL;DR: The Prostate Cancer Clinical Guideline Update Panel is a free resource for clinicians and researchers to assess the need for and ability to evaluate the risks and benefits of utilizing the PSA in men and women diagnosed with prostate cancer.

Guidelines on Prostate Cancer

TL;DR: The introduction of an effective blood test, prostate specific antigen (PSA), has made it possible to diagnose more and more men in an earlier stage where they can be offered potentially curative treatments, and this is the subject of the EAU guidelines on prostate cancer.
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Causes and consequences of comorbidity: a review.

TL;DR: It is found comorbidity in general to be associated with mortality, quality of life, and health care, and the consequences of specific disease combinations depended on many factors.
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The UCLA Prostate Cancer Index: development, reliability, and validity of a health-related quality of life measure.

TL;DR: The UCLA Prostate Cancer Index demonstrated good psychometric properties and appeared to be well understood and easily completed and suggests that these men especially are interested in addressing both the general and disease-specific concerns that impact their daily quality of life.
Journal ArticleDOI

Cancer Survivors in the United States: Age, Health, and Disability

TL;DR: The identification of long-term effects of cancer that contribute to disability and the interventions needed to ameliorate these and their consequences should become a more prominent aspect of the research agenda.
References
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Journal ArticleDOI

Karnofsky performance status revisited: reliability, validity, and guidelines.

TL;DR: Oncologists may train themselves to use the Karnofsky Performance Status in a standard way, which should increase reliability and validity of the KPS and has implications for patients and research studies that use KPS as a stratifying variable.
Journal ArticleDOI

Seasons of survival: reflections of a physician with cancer.

TL;DR: When I was given a diagnosis of cancer, my first thought was not, Will I die?
Journal ArticleDOI

Frequency of sexual dysfunction in "normal" couples.

TL;DR: The number of 'difficulties' reported was more strongly and consistently related to overall sexual dissatisfaction than the number of "dysfunctions."
Journal Article

Measuring quality of life today: methodological aspects.

TL;DR: A table that reviews many available quality of life measures that have been designed for, or frequently used with, people with cancer is reviewed.
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