Journal ArticleDOI
Quantitative surface-enhanced Raman spectroscopy
TLDR
This tutorial review discusses the factors that need to be controlled to generate stable and reproducible SER(R)S calibrations.Abstract:
The purpose of this tutorial review is to show how surface-enhanced Raman (SERS) and resonance Raman (SERRS) spectroscopy have evolved to the stage where they can be used as a quantitative analytical technique. SER(R)S has enormous potential for a range of applications where high sensitivity needs to be combined with good discrimination between molecular targets, particularly since low cost, compact spectrometers can read the high signal levels that SER(R)S typically provides. These advantages over conventional Raman measurements come at the cost of increased complexity and this review discusses the factors that need to be controlled to generate stable and reproducible SER(R)S calibrations.read more
Citations
More filters
Journal ArticleDOI
Surface-enhanced Raman spectroscopy: concepts and chemical applications.
TL;DR: Chemical applications of SERS cover a broad range of topics such as catalysis and spectroelectrochemistry, single-molecule detection, and (bio)analytical chemistry.
Journal ArticleDOI
Cucurbituril-Based Molecular Recognition.
Journal ArticleDOI
SERS Tags: Novel Optical Nanoprobes for Bioanalysis
TL;DR: The fundamental theory of Surface-Enhanced Raman Scattering and the development of Multifunctional Nanoplatforms, a next generation of SERS tags, are studied.
Journal ArticleDOI
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
TL;DR: An outlook of the key challenges in bioanalytical SERS, including reproducibility, sensitivity, and spatial and time resolution is given.
Journal ArticleDOI
A review on the fabrication of substrates for surface enhanced Raman spectroscopy and their applications in analytical chemistry.
TL;DR: This review shows that highly enhancing SERS substrates with a high degree of reliability and reproducibility can now be fabricated at relative low cost, indicating that SERS may finally realize its full potential as a very sensitive tool for routine analytical applications.
References
More filters
Journal ArticleDOI
Surface Enhanced Raman Scattering Enhancement Factors: A Comprehensive Study
TL;DR: In this article, the authors present an in-depth study of surface enhanced Raman scattering (SERS) enhancement factors and cross-sections, including several issues often overlooked, and demonstrate that SERS EFs as low as 107, as opposed to the figure of 1014 often claimed in the literature, are sufficient for SERS applications.
Journal ArticleDOI
A New Method for Fast Preparation of Highly Surface-Enhanced Raman Scattering (SERS) Active Silver Colloids at Room Temperature by Reduction of Silver Nitrate with Hydroxylamine Hydrochloride
Nicolae Leopold,Bernhard Lendl +1 more
TL;DR: In this article, a very effective and simple way to produce silver colloids for surface-enhanced Raman scattering (SERS) is reported. But this method is not suitable for the use of SERS in high-dimensional data.
Book
Surface enhanced vibrational spectroscopy
TL;DR: In this paper, the nature and properties of surface-enhanced vibrational spectra of molecules adsorbed on surfaces that can enhance the absorption and the emission of electromagnetic radiation are discussed.
Journal ArticleDOI
Nanosphere arrays with controlled sub-10-nm gaps as surface-enhanced raman spectroscopy substrates.
TL;DR: As SERS substrates, the as-fabricated Au nanoparticle arrays exhibit high SERS sensitivity, long-term stability, and consistent reproducibility.
Journal ArticleDOI
Rapid and sensitive detection of respiratory virus molecular signatures using a silver nanorod array SERS substrate.
Saratchandra Shanmukh,Les P. Jones,Jeremy D. Driskell,Yiping Zhao,Richard A. Dluhy,Ralph A. Tripp +5 more
TL;DR: This novel SERS assay can detect spectral differences between viruses, viral strains, and viruses with gene deletions in biological media and provides rapid diagnostics for detection and characterization of viruses generating reproducible spectra without viral manipulation.
Related Papers (5)
Probing Single Molecules and Single Nanoparticles by Surface-Enhanced Raman Scattering
Shuming Nie,Steven R. Emory +1 more