Journal ArticleDOI
Recent developments concerning the investigation of exocytosis with amperometry
TLDR
In this article, the authors summarized the recent important results related to the electrochemical detection of vesicular exocytosis by amperometry with microelectrodes over the past three years.About:
This article is published in Current Opinion in Electrochemistry.The article was published on 2021-10-01. It has received 3 citations till now.read more
Citations
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Journal ArticleDOI
Electrochemical Biosensing of Dopamine Neurotransmitter: A Review.
TL;DR: In this article, the authors review the materials (metals and metal oxides, carbon materials, polymers) that are frequently used for the electrochemical biosensing of dopamine and point out their respective advantages and drawbacks.
Journal ArticleDOI
Electrochemical nano-sensing interface for exosomes analysis and cancer diagnosis.
Shijie Li,Qiang Ma +1 more
TL;DR: A review of the recent advance in exosomes detection based on the electrochemical nano-sensing interface, including electrochemical analysis principles, exosome sensing mechanisms, nano-interface construction strategies, as well as the typical diagnosis application is presented in this paper .
Journal ArticleDOI
Electrochemiluminescent Ion-Channeling Framework for Membrane Binding and Transmembrane Activity Assays
The Editors,Uğur Işiklar +1 more
TL;DR: In this paper , an artificial lipoid-supported porin ensemble was used to evaluate the ECL potency in profiling ion-channel activities, and the authors developed a novel ECL model for the evaluation of life-mimicking membrane permeation.
References
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Journal ArticleDOI
A High-Affinity Fluorescent Sensor for Catecholamine: Application to Monitoring Norepinephrine Exocytosis.
TL;DR: AMperometry in conjunction with total internal reflection fluorescence (TIRF) microscopy demonstrates that the sensor can be used to observe destaining of individual chromaffin granules upon exocytosis and results in punctate staining of norepinephrine-enriched Chromaffin cells visualized using confocal microscopy.
Journal ArticleDOI
The evidence for open and closed exocytosis as the primary release mechanism.
Lin Ren,Lisa Mellander,Jacqueline D. Keighron,Ann-Sofie Cans,Michael E. Kurczy,Irina Svir,Alexander Oleinick,Christian Amatore,Andrew G. Ewing +8 more
TL;DR: Evidence is discussed that during exocytosis the vesicle-membrane pore opens to release only a portion of the transmitter content during exocytes and then closes again, which appears to be the main content released during regular exocyTosis.
Journal ArticleDOI
Combined Amperometry and Electrochemical Cytometry Reveal Differential Effects of Cocaine and Methylphenidate on Exocytosis and the Fraction of Chemical Release
TL;DR: Amperometry with nanotip electrodes has been applied to show cocaine and methylphenidate not only trigger declines in vesicle content and exocytotic catecholamine release in a model cell line but also differentially change the fraction of transmitter released from each individual vesicles.
Journal ArticleDOI
Electrochemistry at the Synapse.
TL;DR: Electrochemical measurements of neurotransmitters are compared to optical imaging and mass spectrometry measurements, and while these other techniques provide enhanced spatial or chemical information, electrochemistry is best at monitoring real-time neurotransmission.
Journal ArticleDOI
Counting the Number of Glutamate Molecules in Single Synaptic Vesicles
Yuanmo Wang,Hoda Mashadi Fathali,Devesh Mishra,Tommy Olsson,Jacqueline D. Keighron,Karolina P. Skibicka,Ann-Sofie Cans +6 more
TL;DR: A new enzyme-based amperometric sensor tech-nique for counting of glutamate molecules stored inside single synaptic vesicles is introduced and is comparable to the measured exocytotic quantal glutamate re-lease inAmperometric glutamate sensing in the nucleus accumbens of mouse brain tissue.