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Recent Progress on Molecular Photoacoustic Imaging with Carbon-Based Nanocomposites.

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TLDR
In this paper, the current state of the photoacoustic imaging (PAI) modality, address recent progress on PAI imaging that takes advantage of carbon-based agents, and offer a future perspective on advanced PAI systems using carbonbased agents.
Abstract
For biomedical imaging, the interest in noninvasive imaging methods is ever increasing. Among many modalities, photoacoustic imaging (PAI), which is a combination of optical and ultrasound imaging techniques, has received attention because of its unique advantages such as high spatial resolution, deep penetration, and safety. Incorporation of exogenous imaging agents further amplifies the effective value of PAI, since they can deliver other specified functions in addition to imaging. For these agents, carbon-based materials can show a large specific surface area and interesting optoelectronic properties, which increase their effectiveness and have proved their potential in providing a theragnostic platform (diagnosis + therapy) that is essential for clinical use. In this review, we introduce the current state of the PAI modality, address recent progress on PAI imaging that takes advantage of carbon-based agents, and offer a future perspective on advanced PAI systems using carbon-based agents.

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Organic quantum dots: An ultrasmall nanoplatform for cancer theranostics.

TL;DR: Several varieties of quantum dots used in drug administration are discussed in this paper along with their chemical and physical characteristics and manufacturing methods, as well as their role in biological, medicinal, and theranostic applications.
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Segmentation and Quantitative Analysis of Photoacoustic Imaging: A Review

TL;DR: In this paper , a comprehensive review of segmentation and quantitative methods that have been developed to process photo-acoustic imaging in preclinical and clinical experiments is presented, focusing on the parametric reliability of quantitative analysis for semantic and instance-level segmentation.
References
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Journal ArticleDOI

Soft chemistry of metastable metal chalcogenide nanomaterials.

TL;DR: In this paper, a tutorial review focuses on design principles based on the metastability of metal chalcogenide nanomaterials, such as ion mobility and vacancy, thermal and structural instability, chemical reactivity, and phase transition, together with corresponding soft chemical approaches, including ion exchange, catalytic growth, segregation or coupling, template grafting or transformation, and crystal phase engineering.
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Effective photoacoustic absorption spectrum for collagen-based tissue imaging

TL;DR: The effective PA absorption spectrum contributes to the improvement of the PA image sensitivity by presenting the optimal wavelength of the target samples.
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Endoplasmic reticulum-targeted phototherapy using one-step synthesized trace metal-doped carbon-dominated nanoparticles: Laser-triggered nucleolar delivery and increased tumor accumulation.

TL;DR: A novel, facile, and general synthetic method of carbon-dominated nanoparticles with superior photothermal properties for highly efficient tumor ablation, and the large-organelle (ER and nucleus)-targeted cancer therapeutic strategy may represent an alternative solution for optimizing the anticancer efficacy of nanomaterials.
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Dual-view acoustic-resolution photoacoustic microscopy with enhanced resolution isotropy.

TL;DR: DV-AR-PAM allows the fusion of the dual-view signals, resulting in an enhancement in the resolution isotropy from 29% to 95% within one imaging plane, as demonstrated by simulation results on densely packed particles and experimental results on a single carbon fiber.
Journal ArticleDOI

Real-time Near-infrared Virtual Intraoperative Surgical Photoacoustic Microscopy

TL;DR: A near infrared (NIR) virtual intraoperative surgical photoac acoustic microscopy system that combines a conventional surgical microscope and an NIR light photoacoustic microscopy (PAM) system that can simultaneously visualize PA B-scan images and display enlarged microscopic images on a surgeon's view plane through the ocular lenses of the surgical microscope as augmented reality is developed.
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