Journal ArticleDOI
Regioselective deprotection of 3′,5′-O-acylated pyrimidine nucleosides by lipase and esterase
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TLDR
In this paper, a lipase was found to catalyze the regioselective hydrolysis at the secondary hydroxyl group of 2′-deoxy-3′,5′-di-O-hexanoyl pyrimidine nuclosides.About:
This article is published in Tetrahedron Letters.The article was published on 1989-01-01. It has received 47 citations till now. The article focuses on the topics: Lipase & Triacylglycerol lipase.read more
Citations
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Applications of lipase
TL;DR: This review attempts to present a comprehensive discussion on the present status of this unique group of enzymes in industry, as well as the actual potential.
Journal ArticleDOI
Comparison of lipases by different assays
TL;DR: It is pointed out that for biotechnological applications, a broader definition of lipases is necessary and some lipases proved to be significantly more active with certain artificial substrates at concentrations where no evaluable activity was found with the pH-stat method.
Journal ArticleDOI
The enzymatic synthesis of antiviral agents
TL;DR: The application of biotechnology to the synthesis of antiviral agents including those which are not nucleoside analogues will be discussed.
References
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Protease-catalyzed regioselective esterification of sugars and related compounds in anhydrous dimethylformamide
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Facile enzymatic preparation of monoacylated sugars in pyridine
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