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Relation between stimulation characteristics and clinical outcome in studies using electrical stimulation to improve motor control of the upper extremity in stroke

TLDR
It appears that the specific stimulus parameters may not be crucial in determining the effect of electrical stimulation, and triggered electrical stimulation may be more effective than non-triggered electrical stimulation in facilitating upper extremity motor recovery following stroke.
Abstract
Objective: Electrical stimulation can be applied in a variety of ways to the hemiparetic upper extremity following stroke. The aim of this review is to explore the relationship between characteristics of stimulation and the effect of electrical stimulation on the recovery of upper limb motor control following stroke. Methods: A systematic literature search was performed to identify clinical trials evaluating the effect of electrical stimulation on motor control. The reported outcomes were examined to identify a possible relationship between the reported effect and the following characteristics: duration of stimulation, method of stimulation, setting of stimulation parameters, target muscles and stage after stroke. Results: Nineteen clinical trials were included, and the results of 22 patient groups were evaluated. A positive effect of electrical stimulation was reported for 13 patient groups. Positive results were more common when electrical stimulation was triggered by voluntary movement rather than when non-triggered electrical stimulation was used. There was no relation between the effect of electrical stimulation and the other characteristics examined. Conclusion: Triggered electrical stimulation may be more effective than non-triggered electrical stimulation in facilitating upper extremity motor recovery following stroke. It appears that the specific stimulus parameters may not be crucial in determining the effect of electrical stimulation.

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Journal ArticleDOI

Systematic review of the effect of robot-aided therapy on recovery of the hemiparetic arm after stroke.

TL;DR: It is found that robot-aided therapy of the proximal upper limb improves short- and long-term motor control of the paretic shoulder and elbow in subacute and chronic patients; however, it is found no consistent influence on functional abilities.
Journal ArticleDOI

Interventions for improving upper limb function after stroke

TL;DR: A Cochrane overview of systematic reviews of interventions provided to improve upper limb function after stroke found moderate-quality evidence showed a beneficial effect of constraint-induced movement therapy, mental practice, mirror therapy, interventions for sensory impairment, virtual reality and a relatively high dose of repetitive task practice, suggesting that these may be effective interventions.
Journal Article

Neuromuscular electrical stimulation for skeletal muscle function.

TL;DR: This review covers the aspects of electrical stimulation used for rehabilitation and functional purposes, including frequency, pulse width/duration, duty cycle, intensity/amplitude, ramp time, pulse pattern, program duration, program frequency, and muscle group activated, and how they affect fatigue in the stimulated muscle.
Journal ArticleDOI

Rehabilitation of arm function after stroke. Literature review.

TL;DR: It is shown that exercising the hemiparetic hand and wrist is essential in all stages of a stroke rehabilitation program and new data stemming from neurosciences suggest that ipsilesional corticospinal excitability should be a priority.
Journal ArticleDOI

Iterative Learning Control in Health Care: Electrical Stimulation and Robotic-Assisted Upper-Limb Stroke Rehabilitation

TL;DR: A person who relearns skills after a stroke goes through the same process as someone learning to play tennis or a baby learning to walk, requiring sensory feedback during the repeated practice of a task.
References
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Journal ArticleDOI

Neural Substrates for the Effects of Rehabilitative Training on Motor Recovery After Ischemic Infarct

TL;DR: The results suggest that, after local damage to the motor cortex, rehabilitative training can shape subsequent reorganization in the adjacent intact cortex, and that the undamaged motor cortex may play an important role in motor recovery.
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TL;DR: This review discusses both new measures and new work on more well-established measures, both for use in specific diseases and for more general use, that are slowly being developed.
Journal ArticleDOI

Recovery of upper extremity function in stroke patients: The Copenhagen stroke study

TL;DR: A valid prognosis of UE function can be made within 3 and 6 weeks in patients with mild and severe UE paresis, respectively, and a valid prediction should not be expected after 6 and 11 weeks respectively, in these groups of patients.
Journal ArticleDOI

Functional Reorganization of the Rat Motor Cortex Following Motor Skill Learning

TL;DR: Results demonstrate that motor skill learning is associated with a reorganization of movement representations within the rodent motor cortex.
Journal ArticleDOI

Repetitive training of isolated movements improves the outcome of motor rehabilitation of the centrally paretic hand

TL;DR: The results of the present study emphasize the importance of frequent movement repetition for the motor rehabilitation of the centrally paretic hand and challenge conventional physiotherapeutic strategies that focus on spasticity reduction instead of early initiation of active movements.
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