Relationship between sexual abstinence of men and chromosomally abnormal spermatozoa.
F. Pellestor,B. Sèle +1 more
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The results do not support the hypothesis of an increased risk of aberration with duration of abstinence, and there was no correlation between the length of sexual abstinence and each type of chromosomal abnormality.Abstract:
Epidemiological and mouse cytogenetic studies have suggested the existence of a positive relationship between the frequency of chromosomal abnormalities and the duration of male sexual abstinence. A cytogenetic analysis of human spermatozoa was performed with 4 men after periods of sexual abstinence ranging from 2 to 15 days. Using hamster eggs for penetration, 934 sperm chromosome complements were obtained. The overall frequency of sperm chromosomal abnormalities was 9.4%. There was no correlation between the length of sexual abstinence and each type of chromosomal abnormality. Our results do not support the hypothesis of an increased risk of aberration with duration of abstinence.read more
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Consequences on offspring of abnormal function in ageing gametes
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Differential distribution of aneuploidy in human gametes according to their sex
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L’Equipement chromosomique du spermatozoïde
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References
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A triple-stain technique for evaluating normal acrosome reactions of human sperm.
TL;DR: A triple-stain technique has been developed to score normal acrosome-reacted human sperm in fixed smears and shows that trypan blue is a reliable stain for dead sperm and that Rose Bengal stains only sperm having intact acrosomes.
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A collaborative study of the segregation of inherited chromosome structural rearrangements in 1356 prenatal diagnoses.
André Boué,P. Gallano +1 more
TL;DR: A collaborative study involving 71 European prenatal diagnosis centres has collected 1356 observations on the karyotype of fetal cells in diagnoses performed in couples in which a parent had a balanced structural rearrangement.
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Semen characteristics as a function of age in 833 fertile men.
Daniel Schwartz,Marie-Jeanne Mayaux,Alfred Spira,Marie-Luce Moscato,P. Jouannet,F. Czyglik,G. David +6 more
TL;DR: There is an improvement in semen characteristics up to 25 years of age, followed by a leveling off and a subsequent decrease, and the variation, although small, is highly significant for the morphologic characteristics and prefreeze and postthaw motility.
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The effect of age on the frequency of sperm chromosomal abnormalities in normal men.
Renee H. Martin,Alfred Rademaker +1 more
TL;DR: The results do not support the hypothesis of an increased risk of trisomy with paternal age, and there was a significant negative correlation between age and the frequency of hyperhaploid complements and structural abnormalities.
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Paternal age effect in Down's syndrome.
TL;DR: Comparisons are made between an almost complete Down's syndrome sample from the Copenhagen Metropolitan Area and a randomly selected sample of births from the same area and the same time period.