Retardation of acid diffusion by pig gastric mucus: A potential role in mucosal protection
S.E. Williams,L A Turnberg +1 more
TLDR
The ability of pig gastric mucus to retard diffusion of hydrogen and other small ions was examined in this paper, showing that the diffusion coefficient for hydrogen ions through a known thickness of mucus was four times smaller than the diffusion coefficients through an equivalent thickness of unstirred solution.About:
This article is published in Gastroenterology.The article was published on 1980-08-01 and is currently open access. It has received 160 citations till now. The article focuses on the topics: Mucus & Hydrochloric acid.read more
Citations
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Journal ArticleDOI
Mucin-type glycoproteins.
Ger J. Strous,Jan Dekker +1 more
TL;DR: This review is designed to critically examine relations between structure and function of the different compounds categorized as mucin glycoproteins.
Journal ArticleDOI
Protective effects of prostaglandins against gastric mucosal damage: current knowledge and proposed mechanisms.
TL;DR: Findings suggest that prostaglandins may play a significant role in the pathogenesis of gastric ulceration and may serve an important function in maintaining normal gastric mucosal integrity.
Journal ArticleDOI
Gastroduodenal mucus bicarbonate barrier: Protection against acid and pepsin
Adrian Allen,Gunnar Flemström +1 more
TL;DR: Evidence suggests that under normal physiological conditions, the mucus bicarbonate barrier is sufficient for protection of the gastric mucosa against acid and pepsin and is even more so for the duodenum.
Journal ArticleDOI
Diffusion of macromolecules and virus-like particles in human cervical mucus.
Stuart S. Olmsted,Janet L. Padgett,Ashley I. Yudin,Kevin J. Whaley,Thomas R. Moench,Richard A. Cone +5 more
TL;DR: Electron microscopy of cervical mucus confirmed that the mesh spacing between mucin fibers is large enough for small viruses to diffuse essentially unhindered through mucus, and diffusion by IgM-Fc(5 mu), the Fc pentamer core of an IgM with all 10 Fab moieties removed, was comparably slowed by mucus.
Journal ArticleDOI
Prostaglandins and the gastrointestinal mucosa: Are they important in its function, disease, or treatment?
TL;DR: The involvement of prostaglandins and related compounds in mucosal protection, in ulcer healing, in diarrhea, and in gastrointestinal inflammation is reviewed, with particular reference to the growing body of human data.
References
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Journal ArticleDOI
Active transport of sodium as the source of electric current in the short-circuited isolated frog skin.
Hans H. Ussing,K. Zerahn +1 more
Journal ArticleDOI
Chemical aspects of mucus. General considerations.
BookDOI
Mucus in health and disease
Max Elstein,Dennis V. Parke +1 more
TL;DR: Clinical Aspects of Gastro-Intestinal Mucus.- Ultrastructural Alterations in the Colonic MucUS Layer During Carcinogenesis: A Scanning Electron Microscopy Study.
Journal ArticleDOI
Isolation and Structural Studies of Sulfated Glycoproteins of Hog Gastric Mucosa
Bronislaw L. Slomiany,Karl Meyer +1 more
TL;DR: The carbohydrate chains of the sulfated glycoproteins from hog stomach mucosa are linked to the protein through O-glycosidic bonds involving N-acetylgalactosamine and serine and threonine and some of the linkages between the sugars.
Related Papers (5)
Gastric gel mucus thickness: effect of distention, 16,16-dimethyl prostaglandin e2, and carbenoxolone.
Martin Bickel,Gordon L. Kauffman +1 more