Journal ArticleDOI
Review of Liquid Mixing in Packed Bed Biological Reactors
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The use of residence time distribution analysis to characterize the liquid phase hydrodynamics in bioreactors is reviewed in this article, with special emphasis on packed-bed bioreactor, where tracer selection, the method of data analysis and other uses for the data collected in RTD measurements are discussed.Abstract:
The use of residence time distribution analysis to characterize the liquid phase hydrodynamics in bioreactors is reviewed, with special emphasis on packed bed bioreactors. The importance of tracer selection, the method of data analysis and other uses for the data collected in RTD measurements are discussed.read more
Citations
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Journal ArticleDOI
Development of operating conditions for protein purification using expanded bed techniques: the effect of the degree of bed expansion on adsorption performance.
Y. K. Chang,Howard A. Chase +1 more
TL;DR: It is demonstrated that an adsorption process carried out at a constant degree of bed expansion is more efficient, when characterized by the apparent dynamic binding capacity, than operation at a Constant liquid velocity of 300 cm/h.
Journal ArticleDOI
Improving the hydraulic efficiency of water process tanks using CFD models
TL;DR: The use of guiding walls created flow fields in the tanks with significant volumes of “plug flow”, reduced short-circuiting, smaller re-circulation regions and thus less mixing, and the hydraulic efficiency was significantly improved.
Journal ArticleDOI
Continuous flow hydrogenations using novel catalytic static mixers inside a tubular reactor
A. Avril,Christian H. Hornung,Andrew J. Urban,Darren Fraser,Michael D. Horne,J.-P. Veder,John Tsanaktsidis,Theo Rodopoulos,C. Henry,Dayalan R. Gunasegaram +9 more
TL;DR: In this paper, the authors describe a novel continuous flow reactor concept for organic synthesis using heterogeneous catalysts, which is based on static mixers coated with a catalytic metal layer, which can be inserted into standard stainless steel reactor tubing.
Journal ArticleDOI
Hydrodynamic and biokinetic models of an anaerobic fixed-bed reactor
TL;DR: In this paper, a pilot scale anaerobic fixed-bed process containing a high biomass concentration was studied and the liquid mixing efficiency was good and independent of operating conditions, thanks to the production of biogas.
Journal ArticleDOI
Residence time distribution of the liquid phase in a concentric-tube airlift reactor
Maria Gavrilescu,R. Z. Tudose +1 more
TL;DR: In this article, the residence time distribution (RTD) analysis of liquid phase was performed in a concentric-tube air-lift reactor of 0.07 m3 nominal volume, regarded as a simple unit and discriminating its different sections (riser, downcomer, bottom zone and gas-liquid separator) using tracer response technique.
References
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Journal ArticleDOI
Coalescence of gas bubbles in aqueous solutions of inorganic electrolytes
G. Marrucci,Luigi Nicodemo +1 more
TL;DR: In this paper, a discussion is made of the coalescence phenomena which occur near the distributor and a correlation is attempted which relates the average bubble diameter to the gas flow rate and to a group, G, of the electrolyte properties.
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A Mathematical Model for Dispersion in the Direction Of Flow in Porous Media
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Liquid circulation and mixing characteristics of airlift contactors
TL;DR: In this article, experimentale de quatre contacteurs a boucle externe, dont le rapport des sections du trop plein et du tube de montee se situe dans le domaine 0,11≤A d /A r ≤ 0,69 and de trois contacteur a tubes concentriques, cet.
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Residence time distribution in the liquid phase of trickle flow in packed columns
TL;DR: In this paper, residence time distributions in columns under trickle-flow conditions have been measured with the injection of a tracer, and the results indicated the occurrence of two different elementary mechanisms causing a spread in residence time, viz. an eddy diffusion process and mass exchange with stagnant areas.
Journal ArticleDOI
Mixing in mechanically agitated gas-liquid contactors, bubble columns and modified bubble columns
TL;DR: In this paper, the effect of physical properties of the fluid (surface tension, ionic strength, liquid viscosity) and that of the non-Newtonian behavior on mixing time was studied.