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Role of Streptococcus mutans in human dental decay.

W J Loesche
- 01 Dec 1986 - 
- Vol. 50, Iss: 4, pp 353-380
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This article is published in Microbiological Research.The article was published on 1986-12-01 and is currently open access. It has received 2598 citations till now. The article focuses on the topics: Streptococcus mutans & Streptococcus sobrinus.

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Citations
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Bacterial competition: surviving and thriving in the microbial jungle

TL;DR: A growing body of theoretical and experimental population studies indicates that the interactions within and between bacterial species can have a profound impact on the outcome of competition in nature.
Journal ArticleDOI

Surface Proteins of Gram-Positive Bacteria and Mechanisms of Their Targeting to the Cell Wall Envelope

TL;DR: The mechanisms for both sorting and targeting of proteins to the envelope of gram-positive bacteria are described and the functions of known surface proteins are reviewed.
Journal ArticleDOI

Are dental diseases examples of ecological catastrophes

TL;DR: In this paper, the "ecological plaque hypothesis" was proposed to better describe the relationship between plaque bacteria and the host in health and disease, implying that disease can be prevented not only by directly inhibiting the putative pathogens, but also by interfering with the environmental factors driving the selection and enrichment of these bacteria.
Journal ArticleDOI

Microbial ecology of dental plaque and its significance in health and disease.

TL;DR: It is proposed that disease can be prevented or treated not only by targeting the putative pathogens but also by interfering with the processes that drive the breakdown in homeostasis, and the rate of acid production following sugar intake could be reduced by fluoride, alternative sweeteners, and low concentrations of antimicrobial agents.
Journal ArticleDOI

Genome sequence of Streptococcus mutans UA159, a cariogenic dental pathogen

TL;DR: The genome analysis provides further insight into how S. mutans has adapted to surviving the oral environment through resource acquisition, defense against host factors, and use of gene products that maintain its niche against microbial competitors.
References
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Journal ArticleDOI

Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism

TL;DR: Coupling of Phosphorylation to Electron and Hydrogen Transfer by a Chemi-Osmotic type of Mechanism is described.
PatentDOI

Selective medium for streptococcus mutans

TL;DR: A selective medium was developed for the isolation of Streptococcus mutans from human dental plaque with maximum inhibition of the balance of the streptococcal flora normally encountered on this medium.
Journal ArticleDOI

Actinobacillus actinomycetemcomitans in human periodontal disease

TL;DR: A large body of evidence implicates A. actinomycetemcomitans as an important micro-organism in the etiology of localized juvenile periodontitis including an increased prevalence of the organism in almost all localized juvenileperiodontitis patients and their families compared to other patient groups.
Journal ArticleDOI

The Vipeholm dental caries study; the effect of different levels of carbohydrate intake on caries activity in 436 individuals observed for five years.

TL;DR: The effect of different levels of Carbohydrate Intake on Caries Activity in 436 individuals Observed for five years and the effect of these levels on body composition and activity is compared.
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