Journal ArticleDOI
Roles of zinc(II) ion in phosphatases. A model study with zinc(II)-macrocyclic polyamine complexes
Tohru Koike,Eiichi Kimura +1 more
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This article is published in Journal of the American Chemical Society.The article was published on 1991-11-01. It has received 313 citations till now. The article focuses on the topics: Enzyme model & Zinc.read more
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Artificial receptors for the recognition of phosphorylated molecules
Amanda E. Hargrove,Sonia Nieto,Tianzhi Zhang,Jonathan L. Sessler,Jonathan L. Sessler,Eric V. Anslyn +5 more
TL;DR: Artificial Receptors for the Recognition of Phosphorylated Molecules and their applications in drug discovery and personalized medicine are described.
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Toward the development of metal-based synthetic nucleases and peptidases: a rationale and progress report in applying the principles of coordination chemistry
Eric L. Hegg,Judith N. Burstyn +1 more
TL;DR: Recently, there has been a great interest in designing small metal complexes which are capable of catalytically hydrolyzing deoxyribonucleic acid (DNA), ribonuclear acid (RNA), and protein this article.
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Recent development of zinc-fluorophores
Eiichi Kimura,Tohru Koike +1 more
TL;DR: Following carbonic anhydrase-based biosensors with fluorescent aromatic sulfonamides, a chemosensor, Zinquin, is now extensively used to study the role of intracellular Zn2+ in cellular biology.
Journal ArticleDOI
Highly selective binding of organometallic ruthenium ethylenediamine complexes to nucleic acids: novel recognition mechanisms.
TL;DR: Investigation of nucleic acid derivatives by organometallic ruthenium(II) arene anticancer complexes has revealed that N7-binding is promoted by favorable arene-purine hydrophobic interactions in the associative transition state.