Journal ArticleDOI
Ruthenium catalysed N-alkylation of amines with alcohols
TLDR
The conversion of primary amines into secondary amines has been achieved using alcohols as the alkylating agent, catalysed by [Ru(p-cymene)Cl2]2 and a bidentate phosphine ligand.About:
This article is published in Chemical Communications.The article was published on 2007-02-09. It has received 205 citations till now. The article focuses on the topics: Alkylation & Ruthenium.read more
Citations
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Dehydrogenation as a substrate-activating strategy in homogeneous transition-metal catalysis.
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Hydrogen autotransfer in the N-alkylation of amines and related compounds using alcohols and amines as electrophiles.
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Borrowing hydrogen in the activation of alcohols
TL;DR: In this paper, the metal catalyst returned the hydrogen to the transformed carbonyl compound, leading to an overall process in which alcohols can be converted into amines, compounds containing CC bonds and β-functionalised alcohols.
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Metal-ligand cooperation by aromatization-dearomatization: a new paradigm in bond activation and "green" catalysis.
TL;DR: A range of novel catalytic reactions that were developed guided by these new modes of metal-ligand cooperation are described, including a unique water splitting process, which involves consecutive thermal liberation of H(2) and light-induced liberation of O(2), using no sacrificial reagents, promoted by a pyridine-based pincer ruthenium complex.
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The Catalytic Amination of Alcohols
TL;DR: In this article, the synthesis of amines by the amination of alcohols, by means of the so-called borrowing hydrogen methodology, is presented Compared to other synthetic methodologies for the synthesis, these transformations are highly attractive because often alcohols are readily available starting materials, some of them on a large scale from renewable sources.
References
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Journal ArticleDOI
Facile Conversion of Alcohols into Esters and Dihydrogen Catalyzed by New Ruthenium Complexes
TL;DR: In this paper, an efficient, environmentally benign method for the preparation of esters from alcohols under mild, neutral conditions without the need for carboxylic acid derivatives and condensing agents was developed.
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Ligand effects on dirhodium(II) carbene reactivities. Highly effective switching between competitive carbenoid transformations
Albert Padwa,David J. Austin,Alan T. Price,Mark A. Semones,Michael P. Doyle,Marina N. Protopopova,William R. Winchester,Andrea Tran +7 more
TL;DR: Carboxylate and carboxamide ligands of dirhodium(II) catalysts control chemoselectivity in competitive metal carbene transformations of diazo compounds as mentioned in this paper.
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N-Alkylation of amines with alcohols catalyzed by a Cp*Ir complex
TL;DR: In this article, a new catalytic system consisting of [Cp*IrCl2]2/K2CO3 (Cp *=pentamethylcyclopentadienyl) for the N-alkylation of primary amines with alcohols has been developed.
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Cp*Ir Complex-Catalyzed N-Heterocyclization of Primary Amines with Diols: A New Catalytic System for Environmentally Benign Synthesis of Cyclic Amines
TL;DR: A new efficient method for the N-heterocyclization of primary amines with diols catalyzed by a CpIr complex was developed and a variety of five-, six-, and seven-membered cyclic amines were synthesized in good to excellent yields with the formation of only water as a byproduct.
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Cesium effect: high chemoselectivity in direct N-alkylation of amines
TL;DR: The results demonstrated this methodology was highly chemoselective to favor mono-N-alkylation over dialkylation, offering wide applications in peptidomimetic syntheses.