Journal ArticleDOI
School teacher ratings predictive of psychiatric outcome 25 years later.
Su-chin Serene Olin,Sarnoff A. Mednick,Tyrone D. Cannon,Bjørn Jacobsen,Josef Parnas,Fini Schulsinger,Hanne Schulsinger +6 more
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Teachers' ratings were particularly useful in predicting clinical and psychiatric outcomes 10 and 25 years later, and within this low-risk group, teachers were able to predict which students would develop psychotic disorders.Abstract:
Background The current study examines teacher ratings as a tool for identifying students at risk of developing psychosis. Follow-up and follow-back studies have shown that teachers are capable of identifying individuals who later develop serious mental illness. Method We examine the long-term outcomes for individuals at genetic risk who were identified as showing markedly deviant behaviour and those identified who did not show markedly deviant behaviour. Results Teachers were able to correctly anticipate 35% of students who developed schizophrenia. Furthermore, those identified as showing markedly deviant behaviour had poorer clinical and psychiatric outcomes 10 and 25 years later than those identified as not behaving with marked deviance. Their ratings also differentiated, within the group of people with schizophrenia, which individuals would show evidence of poorer functioning 25 years later. These results were replicated in a group of students not at genetic risk of schizophrenia. Within this low-risk group, teachers were able to predict which students would develop psychotic disorders. Conclusions Teacher ratings were particularly useful in predicting clinical and psychiatric outcomes 10 and 25 years later. The applicability of these findings in early intervention and treatment research is discussed.read more
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Prior juvenile diagnoses in adults with mental disorder: developmental follow-back of a prospective-longitudinal cohort.
Julia Kim-Cohen,Avshalom Caspi,Terrie E. Moffitt,HonaLee Harrington,Barry J. Milne,Richie Poulton +5 more
TL;DR: Most adult disorders should be reframed as extensions of juvenile disorders, in particular, juvenile conduct disorder is a priority prevention target for reducing psychiatric disorder in the adult population.
Journal ArticleDOI
Behavioral and intellectual markers for schizophrenia in apparently healthy male adolescents.
Michael Davidson,Abraham Reichenberg,Jonathan Rabinowitz,Mark Weiser,Zeev Kaplan,Mordehai Mark +5 more
TL;DR: It is demonstrated that simple assessment tools can predict predisposition to schizophrenia in healthy male adolescents and the model's predictive ability does not change as a function of the time elapsed between testing and first hospitalization, suggesting that the model identifies apparently healthy individuals who will manifest the disease later who are not prodromal to psychosis.
Journal ArticleDOI
Implications for the Neural Basis of Social Cognition for the Study of Schizophrenia
TL;DR: How the neural basis of social cognition may inform future clinical research in schizophrenia is discussed, to better elucidate the underlying mechanisms for social cognitive and social behavioral impairments in schizophrenia as well as provide potential targets for treatment and drug development.
Journal ArticleDOI
Nonspecific and attenuated negative symptoms in patients at clinical high-risk for schizophrenia.
TL;DR: Negative symptoms and other nonspecific behavioral abnormalities represent clinically important phenomena in prodromal patients, and may provide insight into pathophysiologic mechanisms in schizophrenia and possible preventive interventions.
Journal ArticleDOI
Early detection and intervention in first-episode schizophrenia: a critical review
Tor K. Larsen,Svein Friis,U. Haahr,Inge Joa,Jan Olav Johannessen,Ingrid Melle,Stein Opjordsmoen,Erik Simonsen,Per Vaglum +8 more
TL;DR: The literature on early intervention in psychosis and relevant studies are reviewed to evaluate relevant studies and to establish a baseline for assessing the effectiveness of these interventions.
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