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Sedentary time and markers of chronic low-grade inflammation in a high risk population.

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TLDR
Novel findings from a high risk population recruited through primary care suggest that sedentary behaviour may influence markers associated with inflammation, independent of MVPA, glycaemia and adiposity.
Abstract
Background Sedentary behaviour has been identified as a distinct risk factor for several health outcomes. Nevertheless, little research has been conducted into the underlying mechanisms driving these observations. This study aimed to investigate the association of objectively measured sedentary time and breaks in sedentary time with markers of chronic low-grade inflammation and adiposity in a population at a high risk of type 2 diabetes mellitus.

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Journal ArticleDOI

Environmental/lifestyle factors in the pathogenesis and prevention of type 2 diabetes

TL;DR: A comprehensive overview of factors contributing to diabetes risk, including aspects of diet quality and quantity, little physical activity, increased monitor viewing time or sitting in general, exposure to noise or fine dust, short or disturbed sleep, smoking, stress and depression, and a low socioeconomic status are presented.
Journal ArticleDOI

Meta-analysis of the relationship between breaks in sedentary behavior and cardiometabolic health

TL;DR: The existing research investigating the relationship between breaks in sedentary behavior with adiposity and cardiometabolic health in adults was systematically reviewed and quantitatively synthesized by this study.

Conducting accelerometer-based activity assessments in field-based research

TL;DR: In this paper, a review of accelerometer-based assessment of physical activity in free-living individuals is presented, focusing on the following issues: product selection, number of accelerometers needed, placement, epoch length, and days of monitoring required to estimate habitual physical activity.
Journal ArticleDOI

Sedentary Lifestyle: Overview of Updated Evidence of Potential Health Risks

TL;DR: Reducing sedentary behaviors and increasing physical activity are both important to promote public health.
References
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Journal ArticleDOI

Mechanisms linking obesity to insulin resistance and type 2 diabetes

TL;DR: In obese individuals, adipose tissue releases increased amounts of non-esterified fatty acids, glycerol, hormones, pro-inflammatory cytokines and other factors that are involved in the development of insulin resistance.
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Calibration of the Computer Science and Applications, Inc. accelerometer.

TL;DR: These data provide a template on which patterns of activity can be classified into intensity levels using the CSA accelerometer, and help to predict energy expenditure at any treadmill speed.
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Interleukin-6 and the acute phase response

TL;DR: Systemic reaction characterized by fever, leukocytosis, increase in erythrocyte sedimentation rate, increases in LeucocyTosis secretion of ACTH and glucocorticoids, and by dramatic changes in the concentration of some plasma ,l' proteins.
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Clinical Application of C-Reactive Protein for Cardiovascular Disease Detection and Prevention

TL;DR: The addition of CRP to standard cholesterol evaluation may provide a simple and inexpensive method to improve global risk prediction and compliance with preventive approaches.
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Elevated C-reactive protein levels in overweight and obese adults.

TL;DR: Higher BMI is associated with higher CRP concentrations, even among young adults aged 17 to 39 years, and these findings suggest a state of low-grade systemic inflammation in overweight and obese persons.
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