Selection theory for marker-assisted backcrossing.
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TLDR
A theory for marker-assisted selection for the proportion of the genome originating from the recurrent parent in a backcross program, carried out after preselection for the target gene(s) is developed.Abstract:
Marker-assisted backcrossing is routinely applied in breeding programs for gene introgression. While selection theory is the most important tool for the design of breeding programs for improvement of quantitative characters, no general selection theory is available for marker-assisted backcrossing. In this treatise, we develop a theory for marker-assisted selection for the proportion of the genome originating from the recurrent parent in a backcross program, carried out after preselection for the target gene(s). Our objectives were to (i) predict response to selection and (ii) give criteria for selecting the most promising backcross individuals for further backcrossing or selfing. Prediction of response to selection is based on the marker linkage map and the marker genotype of the parent(s) of the backcross population. In comparison to standard normal distribution selection theory, the main advantage of our approach is that it considers the reduction of the variance in the donor genome proportion due to selection. The developed selection criteria take into account the marker genotype of the candidates and consider whether these will be used for selfing or backcrossing. Prediction of response to selection is illustrated for model genomes of maize and sugar beet. Selection of promising individuals is illustrated with experimental data from sugar beet. The presented approach can assist geneticists and breeders in the efficient design of gene introgression programs.read more
Citations
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Journal ArticleDOI
Marker-Assisted Selection in Plant Breeding: From Publications to Practice
Yunbi Xu,Jonathan H. Crouch +1 more
TL;DR: Fundamental issues remain to be resolved, particularly regarding complex traits, before marker-assisted selection realizes its full potential in public sector breeding programs, including the development of high throughput precision phenotyping systems for QTL mapping, improved understanding of genotype by environment interaction and epistasis, and development of publicly available computational tools tailored to the needs of molecular breeding programs.
Journal ArticleDOI
A marker-assisted backcross approach for developing submergence-tolerant rice cultivars.
C. N. Neeraja,C. N. Neeraja,Reycel Maghirang-Rodriguez,Alvaro M. Pamplona,Sigrid Heuer,Bertrand C. Y. Collard,Bertrand C. Y. Collard,Endang M. Septiningsih,Georgina V. Vergara,Darlene L. Sanchez,Kenong Xu,Abdelbagi M. Ismail,David J. Mackill +12 more
TL;DR: The results showed that the mega variety Swarna could be efficiently converted to a submergence tolerant variety in three backcross generations, involving a time of two to three years.
Journal ArticleDOI
Breeding schemes for the implementation of genomic selection in wheat (Triticum spp.)
TL;DR: Practical guidelines on the key considerations when implementing genetic selection (GS) are provided, including potential breeding schemes for GS, genotyping considerations, and methods for effective training population design.
Journal ArticleDOI
Association Analysis as a Strategy for Improvement of Quantitative Traits in Plants
TL;DR: A model to describe the association between markers and genes as conditional probabilities in synthetic populations under recurrent selection is proposed, which can be computed on the basis of assumptions related to the history of the population.
Journal ArticleDOI
Traditional and Modern Plant Breeding Methods with Examples in Rice (Oryza sativa L.)
TL;DR: The continuous application of traditional breeding methods in a given species could lead to the narrowing of the gene pool from which cultivars are drawn, rendering crops vulnerable to biotic and abiotic stresses and hampering future progress.
References
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Journal ArticleDOI
Theoretical and empirical issues for marker-assisted breeding of congenic mouse strains.
Paul D. Markel,Pei Shu,Chris Ebeling,George A. Carlson,Deborah L. Nagle,John S. Smutko,Karen J. Moore +6 more
TL;DR: A theoretical evaluation of marker-assisted congenic production is presented and empirical data that support it are provided and this ‘speed congenic’ method is presented in a user-friendly manner to encourage other investigators to pursue this or similar methods of congenicProduction.
Journal ArticleDOI
Marker-Assisted Introgression of Quantitative Trait Loci
TL;DR: When several QTLs are monitored simultaneously, background selection among the limited number of individuals resulting from the foreground selection step accelerates the increase in genomic similarity with the recipient parent, with only limited costs.
Journal ArticleDOI
Using markers in gene introgression breeding programs.
Claude Chevalet,P Mulsant +1 more
TL;DR: It is shown that marker assisted selection may lead to a gain in time of about two generations, an efficiency below previous theoretical predictions, which is used to propose an optimal strategy for selection on the whole genome.
Journal ArticleDOI
Comparison of selection strategies for marker-assisted backcrossing of a gene
TL;DR: Computer simulations were used to compare selection strategies with regard to (i) the proportion of the RPG recovered and (ii) the number of marker data points (MDP) required in a backcross programme designed for introgression of one target allele from a donor line into a recipient line.
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