Journal ArticleDOI
Sensitivity to catecholamines and histamine in the trained and in the untrained human organism and sensitivity changes during digestion
G. Pavlik,R. Frenkl +1 more
TLDR
During digestion the histamine-induced depressor responses of trained subjects tended to approach that of untrained people, and this suggestion was confirmed by the isoproterenol studies, too.Abstract:
Blood pressure and heart rate responses elicited by norepinephrine, epinephrine and histamine were compared before and after duodenal acidification in 27 trained and untrained young healthy men. Before acidification trained subjects showed a lower sensitivity to norepinephrine and histamine and a slightly lower one to epinephrine. In order to explain these phenomena physical training was supposed to affect alpha, respectively beta adrenergic responsivity in a dissimilar manner. This suggestion was confirmed by the isoproterenol studies, too. Duodenal acidification decreased the catecholamine-induced pressor responses. Depressor responses to histamine did not change in the untrained subjects, whereas they increased in the trained group. Thus, during digestion the histamine-induced depressor responses of trained subjects tended to approach that of untrained people.read more
Citations
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Journal ArticleDOI
Differences in cardiovascular responses to isoproterenol in relation to age and exercise training in healthy men.
John R. Stratton,Manuel D. Cerqueira,Robert S. Schwartz,Wayne C. Levy,Richard C. Veith,Steven E. Kahn,Itamar B. Abrass +6 more
TL;DR: It is concluded that there is an age-associated decline in heart rate, blood pressure, ejection fraction, and cardiac output responses to β-adrenergic stimulation with isoproterenol in healthy men.
Journal ArticleDOI
Plasma catecholamines,β-adrenergic receptors, and isoproterenol sensitivity in endurance trained and non-endurance trained volunteers
TL;DR: Higher DHA-binding as observed in M, as well as stroke volume response and glucose increase, may be indicators of a training-dependent rise in sensitivity to catecholamines.
Journal ArticleDOI
Biobehavioral approaches to the treatment of essential hypertension.
James A. Blumenthal,Andrew Sherwood,Elizabeth C. D. Gullette,Anastasia Georgiades,Damon S Tweedy +4 more
TL;DR: Current approaches to the nonpharmacological treatment of high blood pressure are reviewed and outcome studies of exercise, weight loss and dietary modification, and stress management and relaxation therapies are highlighted.
References
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Journal ArticleDOI
Arterial Noradrenaline Concentration during Exercise in Relation to the Relative Work Levels
TL;DR: The noradrenaline levels in arterial blood plasma were followed at rest and during increasing muscular exercise in 5 healthy men and the levels were found to be significantly correlated to the oxygen consumption, measured at submaximal and calculated at supramaximal work.
Journal ArticleDOI
Effect of chronic exercise on myocardial function
James Crews,Earl E. Aldinger +1 more
TL;DR: The degree of cardiomegaly produced in this study is advantageous in the maintenance of homeostasis during exercise and when a large volume or pressure demand is placed on the hypertrophied heart, it is actually capable of responding with a more pronounced Starling effect than the normal nonhypertrophic heart.
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Adrenergic receptors: a personal and practical view*
TL;DR: In this article, it was shown that the receptive mechanism of the adrenergic receptive mechanism is the same as that of the effector cells in the human brain, and that it is the receptor that detects the transmitter and initiates a characteristic response.
Journal ArticleDOI
Acceleration Stress and Effects of Propranolol on Cardiovascular Responses
TL;DR: In this paper, heart rate, arterial pressure and cardiac output were recorded in six physically well-trained, young male volunteers in the sitting position at normal gravity and at 3 G acting in the head-seat direction, before and after beta-adrenergic blockade by propranolol.