Journal ArticleDOI
Smart thin layer chromatography plate.
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TLDR
An innovative thin layer chromatography plate is presented, which integrates a linear array of amorphous silicon photodiodes for real-time qualitative and quantitative chromatographic analysis.Abstract:
We present an innovative thin layer chromatography plate, which integrates a linear array of amorphous silicon photodiodes for real-time qualitative and quantitative chromatographic analysis.read more
Citations
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Journal ArticleDOI
On-chip detection of multiple serum antibodies against epitopes of celiac disease by an array of amorphous silicon sensors
Francesca Costantini,Augusto Nascetti,Riccardo Scipinotti,Fabio Domenici,Simona Sennato,Laura Gazza,Federico Bordi,Norberto Pogna,Cesare Manetti,Domenico Caputo,Giampiero de Cesare +10 more
TL;DR: The sensitivity and the selectivity of the chip for multiplex immunoassays were demonstrated using two gliadin peptides (VEA and DEC), and it was found that the average amount of the bound HRP revealed by the analytical protocol is 3.5 × 10−6 pg μm−2.
Journal ArticleDOI
Microfluidic Chip With Integrated a-Si:H Photodiodes for Chemiluminescence-Based Bioassays
Domenico Caputo,G. de Cesare,Luisa Stella Dolci,Mara Mirasoli,Augusto Nascetti,Aldo Roda,Riccardo Scipinotti +6 more
TL;DR: In this article, the authors presented an on-chip optical detection of chemiluminescent reactions based on the integration of thin film hydrogenated amorphous silicon sensors on a functionalized glass substrate ensuring both a good optical coupling and an optimal separation between biological or chemical reagents and the sensing elements.
Journal ArticleDOI
Amorphous Silicon Photosensors for Detection of Ochratoxin a in Wine
Domenico Caputo,G. de Cesare,Corrado Fanelli,Augusto Nascetti,Alessandra Ricelli,Riccardo Scipinotti +5 more
TL;DR: In this article, the authors used amorphous silicon photometric sensors for the detection of ochratoxin A (OTA) in standard solutions and in contaminated samples of red wine.
Journal ArticleDOI
Multifunctional System-on-Glass for Lab-on-Chip applications
G. Petrucci,Domenico Caputo,Nicola Lovecchio,Francesca Costantini,Ivano Legnini,Irene Bozzoni,Augusto Nascetti,G. de Cesare +7 more
TL;DR: This paper presents, for the first time, the integration on a single glass substrate of different thin film technologies in order to develop a multifunctional platform suitable for on-chip thermal treatments and on- chip detection of biomolecules.
Journal ArticleDOI
Polydimethylsiloxane material as hydrophobic and insulating layer in electrowetting-on-dielectric systems
Domenico Caputo,G. de Cesare,N. Lo Vecchio,Augusto Nascetti,Emanuele Parisi,Riccardo Scipinotti +5 more
TL;DR: Open and closed electrowetting-on-dielectric systems based on a spin coated polydimethylsiloxane (PDMS) layer based on an electronic board controls all the signals needed for the actuation and sensing functionalities of the EWOD systems are presented.
References
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Journal ArticleDOI
Planar chromatography at the turn of the century.
TL;DR: The reasons for selecting thin-layer chromatography for a particular analysis are identified by its attributes: a disposable stationary phase; simultaneous parallel separations; static detection free of time constraints; storage device for chromatographic information; all sample components are observed in the chromatogram.
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Spectral tuned amorphous silicon p-i-n for DNA detection
TL;DR: In this paper, a detection system for fluorochrome labeled DNA based on amorphous silicon technology has been presented, which works without optics for focusing and filtering both the excitation and emitted radiation.
Journal ArticleDOI
Quantitative measurements on wetted thin layer chromatography plates using a charge coupled device camera.
TL;DR: This paper presents the first study of imaging of spots on thin-layer chromatographic plates whilst still wet with solvent, and results are consistent with an effective pathlength significantly longer than the thickness of the sorbent layer.