Journal ArticleDOI
Solvent Dependence of the Hydrodynamical Volume of Dendrimers with a Rubicene Core
TLDR
In this article, a dendrimer with a fluorescent core consisting of a rubicene moiety is synthesized and the hydrodynamical volume is determined in toluene, a good solvent, acetone, a medium quality solvent, and acetonitrile, a poor solvent.Abstract:
Four generations of a dendrimer with a fluorescent core consisting of a rubicene moiety are synthesized. The biexponential nature of fluorescence decay in toluene indicates the presence of two emitting conformations. Molecular modeling suggests that a conformation where the dendrons interact with the core is not improbable. The relative weight of the two decay times indicates that the contribution of that conformation in toluene increases as the dendrimer generation increases. In acetone and acetonitrile however the fluorescence decay is, except for the fourth generation, monoexponential. The hydrodynamical volume of the dendrimer is determined in toluene, a good solvent, acetone, a medium quality solvent, and acetonitrile, a poor solvent, with the time-resolved fluorescence depolarization technique. No change of the hydrodynamical volume is found in toluene in a temperature range between 20 and 94 °C. This suggests that the dendrimers of all the generations are fully expanded in this solvent. In acetonit...read more
Citations
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Journal ArticleDOI
About Dendrimers: Structure, Physical Properties, and Applications
Journal ArticleDOI
Convergent Dendrons and Dendrimers: from Synthesis to Applications
Journal ArticleDOI
Dendrimers in drug research
Ulrik Boas,Peter M. H. Heegaard +1 more
TL;DR: Dendrimers are versatile, derivatisable, well-defined, compartmentalised chemical polymers with sizes and physicochemical properties resembling those of biomolecules e.g. proteins that may be used as drugs for antibacterial and antiviral treatment and have found use as antitumor agents.
Journal ArticleDOI
Dendritic Encapsulation of Function: Applying Nature's Site Isolation Principle from Biomimetics to Materials Science.
Stefan Hecht,Jean M. J. Fréchet +1 more
TL;DR: The recent progress in the synthesis of dendrimer-encapsulated molecules and their study by a variety of techniques is discussed, and a natural design principle that contributes to bridging the gap between biology and materials science is focused on.
Journal ArticleDOI
Mechanism of Charging and Supercharging Molecules in Electrospray Ionization
TL;DR: It is demonstrated that in the absence of other factors, the surface tension of the electrospray droplet late in the desolvation process is a significant factor in determining the overall analyte charge.
References
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Journal ArticleDOI
Preparation of polymers with controlled molecular architecture. A new convergent approach to dendritic macromolecules
TL;DR: In this article, a convergent growth approach to topological macromolecules based on dendritic fragments is described, where polyether dendric fragments are prepared by starting from what will become the periphery of the molecule and progressing inward.
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Molecular Volumes and the Stokes-Einstein Equation.
TL;DR: In this article, a simple notion of the volume of a molecule was adopted to produce an empirical correction factor for the Stokes equation to enable one to apply it to molecules down to two angstroms in radius.
Journal ArticleDOI
Encapsulation of guest molecules into a dendritic box.
TL;DR: The synthesis and characterization of dendritic boxes, based on the construction of a chiral shell of protected amino acids onto poly(propyleneimine) dendrimers with 64 amine end groups, is reported here, showing that a dense shell with solid-phase character is formed.
Journal ArticleDOI
Self-Assembling Dendrimers
TL;DR: The synthesis of molecules containing two isophthalic acid units covalently attached to a rigid aromatic spacer is described, which produces hydrogen-bonded macromolecular assemblies comparable to that of small proteins.
Journal ArticleDOI
Unique behavior of dendritic macromolecules: intrinsic viscosity of polyether dendrimers
Thomas H. Mourey,S. R. Turner,Michael Rubinstein,J. M. J. Frechet,Craig J. Hawker,Karen L. Wooley +5 more
TL;DR: In this article, the convergent growth approach is applied to polyether dendrimers with coupled molecular weight sensitive detection and the results show that the results are as narrow as those of polystyrene with M w /M n ≃ 1.04.