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Spectral analysis of heart rate variability signal and respiration in diabetic subjects

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TLDR
Methods of processing ECG and respiration signals which aim at detecting parameters whose values may be correlated to normal and diabetic subjects with or without cardiovascular autonomic neuropathy (CAN), and developed spectral parameters seem sensitive enough to differentiate between normal and pathological subjects.
Abstract
The paper deals with methods of processing ECG and respiration signals which aim at detecting parameters whose values may be correlated to normal and diabetic subjects with or without cardiovascular autonomic neuropathy (CAN). Beatto-beat R-R duration values of the ECG and discrete series of respiration are obtained from original signals using a recognition algorithm. Power spectrum analysis (autospectra, cross-spectra and coherence via autoregressive modelling) is carried out on segments of about 200 consecutive cardiac cycles. Spectral parameters of the R-R variability signal are obtained as follows: total power, power of low-frequency (LF) and high-frequency (HF) components, power of the signal which is (or is not) coherent with respiration, in absolute or in percentage values. The experimental protocol considers 40 diabetic patients (21 of whom have diabetic neuropathy) and 14 normals in three different conditions: resting, standing and controlled respiration. The developed spectral parameters seem sensitive enough to differentiate between normal and pathological subjects. These parameters may constitute a quantitative means to be edded to the classical diabetic tests for the diagnosis of cardiovascular autonomic neuropathy.

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Citations
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Journal ArticleDOI

Heart rate variability: Origins, methods, and interpretive caveats

TL;DR: In this article, the authors examined the physiological origins and mechanisms of heart rate variability, considered quantitative approaches to measurement, and highlighted important caveats in the interpretation of heart rates variability, and outlined guidelines for research in this area.
Journal ArticleDOI

Heart rate variability

TL;DR: This chapter will review the methodology ofHRV measurement, the physiological basis of HRV and the factors influencing HRV.
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Heart Rate Variability.: Standards of Measurement, Physiological Interpretation, and Clinical Use: Task Force of The European Society of Cardiology and the North American Society for Pacing and Electrophysiology

TL;DR: In this paper, the authors reviewed the physiology, technical problems of assessment, and clinical relevance of heart rate variability in patients who have survived an acute myocardial infarction and concluded that heart rate is the single most important predictor of those patients who are at high risk of sudden death or serious ventricular arrhythmias.
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Power spectrum analysis of heart rate fluctuation: a quantitative probe of beat-to-beat cardiovascular control

TL;DR: It is shown that sympathetic and parasympathetic nervous activity make frequency-specific contributions to the heart rate power spectrum, and that renin-angiotensin system activity strongly modulates the amplitude of the spectral peak located at 0.04 hertz.
Journal ArticleDOI

Power spectral analysis of heart rate and arterial pressure variabilities as a marker of sympatho-vagal interaction in man and conscious dog.

TL;DR: The spontaneous beat-to-beat oscillation in R-R interval during control recumbent position, 90° upright tilt, controlled respiration and acute and chronic β-adrenergic receptor blockade was analyzed, indicating that sympathetic nerves to the heart are instrumental in the genesis of low-frequency oscillations in R -R interval.
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