Stewart and beyond: New models of acid-base balance
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TLDR
This review will present both the traditional and the Stewart models of acid-base balance and then derive each using an "ion equilibrium method" which may be useful toward the understanding of complex acid- base disorders.About:
This article is published in Kidney International.The article was published on 2003-09-01 and is currently open access. It has received 179 citations till now.read more
Citations
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Biochemistry of exercise-induced metabolic acidosis
TL;DR: The development of acidosis during intense exercise has traditionally been explained by the increased production of lactic acid, causing the release of a proton and the formation of the acid salt.
Biochemistry of exercise-induced metabolic acidosis
TL;DR: This review presents clear evidence that there is no biochemical support for lactate production causing acidosis, and there is a wealth of research evidence to show that acidosis is caused by reactions other than lactateproduction.
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Evaluation of the ruminant serum chemistry profile.
TL;DR: The first sections of this article introduce concepts important to all laboratory tests, such as sample collection and handling, reference intervals, and quality control.
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Clinical review: Reunification of acid–base physiology
TL;DR: This review explores how the new and older approaches to acid–base physiology can be reconciled and combined to result in a powerful bedside tool.
Aldosterone regulated acid-base transport in the collecting duct
TL;DR: The renal collecting system serves the fine-tuning of renal acid–base secretion and Dysregulation of intercalated cell function or abundance causes various syndromes of distal renal tubular acidosis underlining the importance of these processes for acid-base homeostasis.
References
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Journal ArticleDOI
The determination of gases in blood and other solutions by vacuum extraction and manometric measurement. I.
TL;DR: The manometric apparatus is used for air and general gas analysis, and combined determination of carbon dioxide, oxygen, and carbon monoxide, together with microanalyses, is shown.
Journal ArticleDOI
The nature of the hydrated excess proton in water
TL;DR: In this article, the authors used ab initio path integral simulations to address the question that the hydrated proton forms a fluxional defect in the hydrogen-bonded network, with both H9O4+ and H5O2+ occurring only in the sense of "limiting" or "ideal" structures.
Journal ArticleDOI
Modern quantitative acid–base chemistry
TL;DR: An approach to acid-base which revolutionizes the authors' ability to understand, predict, and control what happens to hydrogen ions in living systems is outlined and some of its most useful implications are suggested.
Journal ArticleDOI
The nature and transport mechanism of hydrated hydroxide ions in aqueous solution
TL;DR: The solution structures and transport mechanisms of hydrated hydroxide are reported from first-principles computer simulations that explicitly treat quantum and thermal fluctuations of all nuclei and find that the transport mechanism differs significantly from the proton hole picture.
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Rapid saline infusion produces hyperchloremic acidosis in patients undergoing gynecologic surgery
TL;DR: Infusion of 0.9% saline, but not lactated Ringer's solution, caused a metabolic acidosis with hyperchloremia and a concomitant decrease in the strong ion difference and the amount of weak plasma acid.