Journal ArticleDOI
Stimulatory and inhibitory effects of progesterone on the release of pituitary ovulating hormone in the rabbit.
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A study of the effects of progesterone on ovulation in the rabbit reveals that the steroid at first facilitates and subsequently inhibits the release of pituitary ovulating hormone.Abstract:
A study of the effects of progesterone on ovulation in the rabbit reveals that the steroid at first facilitates and subsequently inhibits the release of pituitary ovulating hormone. Forty estrous or estrogen-primed female rabbits were treated with 2 ing. progesterone in oil subcutaneously and subjected within 1–4 hours to glass-rod stimulation of the vagina; 11 of them ovulated as compared with only 2⁄30 controls. Mating or intravenous copper acetate, within 4 hours after injection of progesterone, stimulated ovulation in all of 10 estrous rabbits. A few progesterone-treated females ovulated “spontaneously.” The facilitation appeared to depend on synergism of progesterone with estrogen; 10 anestrous animals failed to respond to progesterone and vaginal stimulation by ovulating. Twenty-four hours after treatment with progesterone, 21 initially estrous or estrogen-primed rabbits were allowed to mate; only 14 would permit copulation and 10 of these failed to ovulate. None of 10 estrogen-progesterone-treated ...read more
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Journal ArticleDOI
Relative roles of the pituitary, follicle cells, and progesterone in the induction of oocyte maturation in Rana pipiens
TL;DR: Results indicate that pituitary gonadotropin acts on the follicle cells to stimulate them to release a hormone that directlyact on the oocyte to induce maturation.
Journal ArticleDOI
Progesterone: its role in the central nervous system as a facilitator and inhibitor of sexual behavior and gonadotropin release.
H. H. Feder,Babetta L. Marrone +1 more
TL;DR: It is suggested that progesterone-sensitive neural systems operate with a precision that is attributable more to interneuronal channeling of information to or from estrogen-sensitive areas than to intranuclear programming of biochemical events.
Book ChapterDOI
Interrelations between progesterone and the ovary, pituitary, and central nervous system in the control of ovulation and the regulation of progesterone secretion.
TL;DR: It is concluded that the interaction of a number of factors has the gerneral effect of facilitating ovulation and of setting up conditions such that once ovulation has occurred the activity of the corpus luteum other things being equal tends to make ovulation recur regularly.
Journal ArticleDOI
Induction of estrus: Estrogen-progesterone interactions
TL;DR: Accumulating evidence indicates that progesterone can have both facilitatory and inhibitory effects on sexual receptivity and ovulation, but only when administered chronically and at high dose levels.
Journal ArticleDOI
Progesterone: Inhibition of rodent sexual behavior
TL;DR: Inhibition of receptive behavior has been induced by progesterone implanted in the rodent midbrain, but not by implants in other regions of the CNS, which correlates with the observation that rodent mid brain concentrates progester one more than other brain regions.
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