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Stromomyoma of the uterus

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TLDR
The similarity between the tumor and those reported in the literature raises the possibility that “uterine tumor resembling ovarian sex‐cord tumors” are actually stromomyomas, and the term “Stromomyoma” is proposed to designate this peculiar uterine tumor.
Abstract
We present a solitary uterine tumor that occurred in a 28-year-old woman who complained of vaginal bleeding Grossly, the tumor was well circumscribed and composed of lobulated tissue that varied from yellow, tan and soft, to white and rubbery At the light microscopic level, areas identical to those described and interpreted as sex-cord differentiation in a group of closely similar uterine tumors were found and obtained for electron microscopic study Ultrastructurally, there were two basic types of cells, neither of which can be interpreted as sex-cord derivatives Cells that closely resembled the predominant components of Clement and Scully's group I tumors were similar to the normal endometrial stromal cells Cells that formed plexiform cords demonstrated features diagnostic of smooth muscle cells Cellular contents in cells comprising the tubular structures resembling that interpreted as indistinguishable from that of a Sertoli-cell tumor (tubular androblastoma) were probably smooth muscle cells We propose the term "Stromomyoma" to designate this peculiar uterine tumor The similarity between our tumor and those reported in the literature raises the possibility that "uterine tumor resembling" ovarian sex-cord tumors" are actually stromomyomas

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Book ChapterDOI

Mesenchymal Tumors of the Uterus

TL;DR: Purely mesenchymal tumors, such as those derived from smooth muscle and endometrial stroma, are considered, as are benign and malignant neoplasms in which there are mixtures of epithelium and connective tissue.
Journal ArticleDOI

h-Caldesmon expression effectively distinguishes endometrial stromal tumors from uterine smooth muscle tumors.

TL;DR: H-caldesmon appears to be a more sensitive and specific marker of smooth muscle differentiation in the uterus than desmin and may be a useful tool for distinguishing and classifying uterine mesenchymal tumors.
Journal ArticleDOI

Uterine tumors resembling ovarian sex cord tumors are polyphenotypic neoplasms with true sex cord differentiation.

TL;DR: The morphologic and immunohistochemical findings in uterusine tumors resembling ovarian sex cord tumors strongly support that these unusual uterine tumors are polyphenotypic neoplasms with true sex cord differentiation.
Journal ArticleDOI

Mixed endometrial stromal and smooth muscle tumors of the uterus: a clinicopathologic study of 15 cases.

TL;DR: Mixed endometrial stromal and smooth muscle tumors should be distinguished from highly cellular leiomyomas, pure endomet trial stroma tumors, and "uterine tumors resembling ovarian sex cord tumors," at least until knowledge of their clinicopathologic features is more complete.
Journal ArticleDOI

Lifetime expression of stem cell markers in the uterine endometrium.

TL;DR: It is found that stem cells are present continuously in the uterine endometrium from the fetal period and seem to be located mainly in the stroma of the basalis and to be independent of hormonal regulation to avoid cyclic shedding.
References
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Journal ArticleDOI

Uterine Tumors Resembling Ovarian Sex-cord Tumors: A Clinicopathologic Analysis of Fourteen Cases

TL;DR: Uterine tumors with histologic resemblances to ovarian sex-cord tumors were encountered in 14 women in the fourth to sixth decades of life, most of whom had abnormal vaginal bleeding and enlarged uteri suggesting leiomyomas, and an origin from endometrial stromal cells is postulated.
Journal ArticleDOI

A comparative ultrastructural study of leiomyosarcoma, cellular leiomyoma, and leiomyoma of the uterus

TL;DR: It is suggested that the leiomyoma and leoomyosarcoma are distinct entities and that the cellular leuomyoma represents a variety of the common leiomysoma rather than an intermediate form between leiomers and leioms.
Journal ArticleDOI

Ultrastructure of the human endometrial stroma cell during the menstrual cycle.

TL;DR: The ultrastructure of endometrial stromal cells of normal healthy women in reproductive age is described on days 5, 10, 15, 20, and 25 of the menstrual cycle to show distinctive ultrastructural changes that can be correlated with states of proliferation, differentiation, and maturation.
Journal Article

The ultrastructure of smooth muscle tumors with a consideration of the possible relationship of glomangiomas, hemangiopericytomas, and cardiac myxomas.

TL;DR: The light microscopic and ultrastructural findings in these four sarcomas may be due to sampling problems likely to be encountered in poorly differentiated tumors or simply the failure of development of specific ultrastructureural features in the face of a characteristic growth pattern at the light microscopic level.
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