Journal ArticleDOI
Studies of regulatory metabolism in Moniezia expansa: general considerations.
TLDR
Levels of metabolic intermediates in worms incubated aerobically and anaerobically are presented, and ‘cross-over’ plots and calculations of apparent equilibrium constants identify hexokinase, phosphofructokinase and pyruvate kinase as regulatory.About:
This article is published in International Journal for Parasitology.The article was published on 1975-04-01. It has received 40 citations till now. The article focuses on the topics: Gluconeogenesis & Pyruvate kinase.read more
Citations
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Journal ArticleDOI
Intermediary carbohydrate metabolism in protoscoleces of Echinococcus granulosus (horse and sheep strains) and E. multilocularis.
Donald P. McManus,J. D. Smyth +1 more
TL;DR: The steady state content of ATP and the ATP/AMP ratios are low in the three organisms, suggesting a low rate of ATP utilization in each and the tricarboxylic acid cycle may play a more important role in carbohydrate metabolism and energy production in the latter parasites.
Journal ArticleDOI
A possible biochemical mode of action for benzimidazole anthelmintics
R.O. McCracken,W.H. Stillwell +1 more
TL;DR: These experiments indicate that the benzimidazole anthelmintics are lipid-soluble proton conductors that are effective in artificial and natural rat liver mitochondria membrane systems.
Book ChapterDOI
Carbon Dioxide Utilisation, and the Regulation of Respiratory Metabolic Pathways in Parasitic Helminths
TL;DR: The chapter distinguishes among the enzymes, when each of the major groups of parasitic helminths is considered from the point of view of CO2 utilization, and summarizes the roles that phosphoenolpyruvate carboxykinase (PEPCK), malic enzyme (ME), and pyruvATE carboxylase play in intermediary metabolism.
Journal ArticleDOI
Studies of regulatory metabolism in Moniezia expansa: Effects of cambendazole and mebendazole
M.S. Rahman,Christopher Bryant +1 more
TL;DR: Anaerobically and in the presence of glucose, both drugs inhibited glucose uptake and increased glycogen utilisation and adenine nucleotides but the formation of end products was unaffected.
Journal ArticleDOI
Changes in energy metabolism due to anthelmintics in Fasciola hepatica maintained in vitro
TL;DR: The effects of rafoxanide, nitroscanate and mebendazole on oxidative pathways in whole F. hepatica maintained in a simple salt solution have been examined and the mechanisms of action of the drugs are discussed.
References
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Journal Article
Protein Measurement with the Folin Phenol Reagent
TL;DR: Procedures are described for measuring protein in solution or after precipitation with acids or other agents, and for the determination of as little as 0.2 gamma of protein.
Journal ArticleDOI
A simple efficient liquid scintillator for counting aqueous solutions in a liquid scintillation counter
TL;DR: A modification of the naphthalene-dioxane-PPO liquid scintillator has been described which will allow up to 3.0 ml of an aqueous solution to be counted as mentioned in this paper.
Book ChapterDOI
d-Glucose: Determination with Hexokinase and Glucose-6-phosphate Dehydrogenase
TL;DR: This chapter discusses an enzymatic method for the determination of D -glucose with hexokinase and glucose-6-phosphate dehydrogenase, a method based on the optical method developed by O. Warburg and his collaborators.
Book ChapterDOI
[65] Assays of intermediates of the citric acid cycle and related compounds by fluorometric enzyme methods
TL;DR: This chapter is based on the assays of intermediates of the citric acid cycle and related compounds by fluorometric enzyme methods based on instruments capable of giving a full-scale deflection of the recorder with 0.25μM NADH, with a noise level less than 2%.
Book ChapterDOI
l-(+)-Lactate: Determination with Lactic Dehydrogenase and DPN
TL;DR: This chapter discusses the enzymatic determination of L-(+)-lactate with lactic dehydrogenase (LDH) and diphosphopyridine nucleotide (DPN).
Related Papers (5)
Carbon Dioxide Utilisation, and the Regulation of Respiratory Metabolic Pathways in Parasitic Helminths
Studies on glycolysis in the muscle tissue of Ascaris lumbricoides (nematoda)
J. Barrett,Isidoros Beis +1 more