Journal ArticleDOI
Successful small-bowel/liver transplantation
David R. Grant,William Wall,Mimeault R,Robert Zhong,Cameron N. Ghent,Bertha Garcia,Calvin R. Stiller,John Duff +7 more
TLDR
Small-bowel/liver grafting is feasible for patients with the short-gut syndrome and associated liver disorders and further experience is needed to determine the specific risks, benefits, and general applicability of this procedure.About:
This article is published in The Lancet.The article was published on 1990-01-27. It has received 386 citations till now. The article focuses on the topics: Liver transplantation & Short bowel syndrome.read more
Citations
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Journal ArticleDOI
Intestinal permeability: an overview.
TL;DR: There is a need for integrated research into the basic mechanisms of regulatory control of the intestinal barrier function and the potential and possible shortcomings of noninvasive tests of intestinal permeability.
Journal ArticleDOI
Cell migration and chimerism after whole-organ transplantation: The basis of graft acceptance
Thomas E. Starzl,Anthony J. Demetris,Massimo Trucco,Noriko Murase,Camillo Ricordi,Suzanne T. Ildstad,H. Ramos,Satoru Todo,Andreas G. Tzakis,John J. Fung,Michael A. Nalesnik,Adriana Zeevi,William A. Rudert,Mirjana Kocova +13 more
TL;DR: It is proposed recently that the exchange of migratory leukocytes between the transplant and the recipient with consequent long-term cellular chimerism in both is the basis for acceptance of all whole-organ allografts and xenograftS.
Journal ArticleDOI
Clinical Intestinal Transplantation: A Decade of Experience at a Single Center
Kareem Abu-Elmagd,Jorge Reyes,Geoffrey Bond,George V. Mazariegos,Tong Wu,Noriko Murase,Rakesh Sindhi,D Martin,Joanne Colangelo,Marsha Zak,Douglas Janson,Mohamed Ezzelarab,Igor Dvorchik,Maria Parizhskaya,Melvin Deutsch,Anthony J. Demetris,John J. Fung,Thomas E. Starzl +17 more
TL;DR: The survival rates after intestinal transplantation have cumulatively improved during the past decade, and with the management strategies currently under evaluation, intestinal transplant procedures have the potential to become the standard of care for patients with end-stage intestinal failure.
Journal ArticleDOI
Intestinal transplant registry report: global activity and trends.
David R. Grant,Kareem Abu-Elmagd,Kareem Abu-Elmagd,George V. Mazariegos,Rodrigo Vianna,Alan Norman Langnas,Richard S. Mangus,Douglas G. Farmer,F. Lacaille,Kishore Iyer,Thomas M. Fishbein +10 more
TL;DR: Waiting at home for IT, the use of induction immune‐suppression therapy, inclusion of a liver component and maintenance therapy with rapamycin were associated with better graft survival and case volumes have recently declined.
Journal ArticleDOI
Ectoines in cell stress protection: uses and biotechnological production.
José M. Pastor,Manuel Salvador,Montserrat Argandoña,Vicente Bernal,Mercedes Reina-Bueno,Laszlo N. Csonka,José L. Iborra,Carmen Vargas,Joaquín J. Nieto,Manuel Cánovas +9 more
TL;DR: The state of the art in ectoines uses and applications and industrial scale production using bacteria is summarized, emphasizing the importance of reactor design and operation strategies, together with the metabolic engineering aspects and the need for feedback between wet and in silico work to optimize bioproduction.
References
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Journal ArticleDOI
Induction of Immunological Tolerance by Porcine Liver Allografts
Roy Y. Calne,R. A. Sells,Pena,D. R. Davis,P. R. Millard,B. M. Herbertson,R.M. Binns,D. A. L. Davies +7 more
TL;DR: It is suggested that allogeneic liver can induce immunological tolerance in immunologically mature pigs and help protect donor specific tissue from rejection.
Journal Article
The gut: a central organ after surgical stress.
Douglas W. Wilmore,Robert J. Smith,S. T. O'Dwyer,Danny O. Jacobs,Thomas R. Ziegler,Xian-Dong Wang +5 more
TL;DR: It is anticipated that a combination of hormones and specific nutrients will provide optimal support of the gut mucosa in the severely ill patient and glutamine-containing parenteral feedings are associated with increased mucosal cellularity and improved survival after gut injury.
Journal ArticleDOI
Transplantation of Multiple Abdominal Viscera
Thomas E. Starzl,Marc I. Rowe,Satoru Todo,Ronald Jaffe,Andreas G. Tzakis,Allen L. Hoffman,Carlos O. Esquivel,Kendrick A. Porter,Raman Venkataramanan,Leonard Makowka,Rene Duquesnoy +10 more
TL;DR: Two children with the short-gut syndrome and secondary liver failure were treated with evisceration and transplantation en bloc of the stomach, small intestine, colon, pancreas, and liver, and the constituent organs of the homograft functioned and maintained their morphological integrity throughout the 193 days of survival.
Journal ArticleDOI
Absorption of 151chromium-labeled ethylenediaminetetraacetate in inflammatory bowel disease
TL;DR: Intestinal permeability was assessed in patients with inflammatory bowel disease by measuring the urine excretion of 151 chromium-labeled ethylenediaminetetraacetate over periods up to 24 h after oral administration to appear to be a sensitive, noninvasive test for assessing small intestinal integrity.
Journal ArticleDOI
Graft rejection and graft-versus-host disease: mirror images.
TL;DR: Attempts to suppress graft rejection or GvHD are likely to increase the reciprocal outcomes unless additional measures are instituted, and these events are inversely correlated.
Related Papers (5)
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Transplantation of small bowel in the rat: technical and immunological considerations.
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