An attempt to synthesize 4-ethylcyclohex-2-enone by a Robinson-type ring closure gave a mixture of conjugated and non-conjugated ketones from which the conjugated isomer was isolated. 4-Ethylcyclohex-3-enone on treatment with acid yielded the same mixture of ketones. Pyrolysis of 4-carboxy-4-vinylheptanedioic acid with barium carbonate formed 4-ethylidenecyclohexanone.

Natural sandalwood oil, a unique and valuable ingredient in fine perfumery, has been the focus of scientific interest for many years. Due to its scarcity and its high price, the search for novel synthetic raw materials imitating the characteristic odor profile of sandalwood oil is as challenging as ever. In this context, the preparation of the novel sandalwood odorants 26, 33, and 39 will be discussed, including their sensory properties and structure-odor relationship.

Syntheses in the cyclohexanone series. II. The syntheses of 4-Ethylcyclohex-2- enone, 4-Ethylcyclohex-3-enone, and 4-Ethylidenecyclohexanone

Citations

Recent developments in the chemistry of sandalwood odorants

Intermediates for the synthesis of indole alkaloids. Synthesis of tetrahydrocarbazole derivatives

Synth. in der cyclohexanon-reihe 2. mitt. synth. von 4-aethyl-cyclohexen-(2)-on, 4-aethyl-cyclohexen-(3)-on und 4-aethyliden-cyclohexanon

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