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Open AccessJournal ArticleDOI

Temporally Structured Replay of Awake Hippocampal Ensemble Activity during Rapid Eye Movement Sleep

Kenway Louie, +1 more
- 01 Jan 2001 - 
- Vol. 29, Iss: 1, pp 145-156
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TLDR
It is demonstrated that long temporal sequences of patterned multineuronal activity suggestive of episodic memory traces are reactivated during REM sleep, which may be important for memory processing and provides a basis for the electrophysiological examination of the content of dream states.
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This article is published in Neuron.The article was published on 2001-01-01 and is currently open access. It has received 1058 citations till now. The article focuses on the topics: Non-rapid eye movement sleep & Sleep spindle.

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Learning Induces Long-Term Potentiation in the Hippocampus

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References
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Journal ArticleDOI

A synaptic model of memory: long-term potentiation in the hippocampus

TL;DR: The best understood form of long-term potentiation is induced by the activation of the N-methyl-d-aspartate receptor complex, which allows electrical events at the postsynaptic membrane to be transduced into chemical signals which, in turn, are thought to activate both pre- and post Synaptic mechanisms to generate a persistent increase in synaptic strength.
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The hippocampus as a spatial map. Preliminary evidence from unit activity in the freely-moving rat

TL;DR: Preliminary observations on the behaviour of hippocampusal units in the freely moving rat provide support for this theory of hippocampal function.
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Memory and the hippocampus: A synthesis from findings with rats, monkeys, and humans.

TL;DR: The role of the hippocampus is considered, which is needed temporarily to bind together distributed sites in neocortex that together represent a whole memory.
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Reactivation of hippocampal ensemble memories during sleep.

TL;DR: In this paper, large ensembles of hippocampal "place cells" were recorded from three rats during spatial behavioral tasks and in slow-wave sleep preceding and following these behaviors, showing an increased tendency to fire together during subsequent sleep, in comparison to sleep episodes preceding the behavioral tasks.
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Dynamics of the hippocampal ensemble code for space

TL;DR: Parallel recording methods outlined here make possible the study of the dynamics of neuronal interactions during unique behavioral events, which suggests that new spatial information creates conditions in the hippocampal circuitry that are conducive to the synaptic modification presumed to be involved in learning.
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