Testing for anatomically specified regional effects.
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A simple method is presented that allows statistical inferences to be made about the significance of regional effects in statistical parametric maps when the approximate location of the effect is specified in advance using the spatial extent or volume of the nearest activated region.Abstract:
r Abstract: We present a simple method that allows statistical inferences to be made about the significance of regional effects in statistical parametric maps (SPMs) when the approximate location of the effect is specified in advance. The test can be thought of as analogous to assessing activations with uncorrected P values based on the height of SPMs but, in this instance, using the spatial extent or volume of the nearest activated region. The advantage of the current test is that it eschews a correction for multiple comparisons even though the exact location of the expected activation may not be known. Hum. Brain Mapping 5:133-136, 1997. r 1997 Wiley-Liss, Inc.read more
Citations
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Journal ArticleDOI
Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia
Susan Whitfield-Gabrieli,Heidi W. Thermenos,Snezana Milanovic,Ming T. Tsuang,Stephen V. Faraone,Robert W. McCarley,Martha E. Shenton,Alan I. Green,Alfonso Nieto-Castanon,Peter S. LaViolette,Joanne Wojcik,John D. E. Gabrieli,Larry J. Seidman +12 more
TL;DR: Among patients, the magnitude of MPFC task suppression negatively correlated with default connectivity, suggesting an association between the hyperactivation and hyperconnectivity in schizophrenia.
Book ChapterDOI
Statistical parametric mapping.
Abstract: This chapter deals with the experimental design and analysis of functional brain imaging studies. It considers the neurobiological motivations for different designs and describes some standard approaches, developed to analyse the ensuing data. Functional neuroimaging (positron emission tomography - PET and functional magnetic resonance imaging fMRI) are generally used to make inferences about functional anatomy on the basis of evoked patterns of cortical activity. Functional anatomy refers to the anatomical organisation of the brain, as it relates to function. It involves an understanding of what each part of the brain does, and how different brain systems interact to support various sensori-motor and cognitive functions. This chapter discusses how this understanding is attained from the perspective of design and analysis of neuroimaging data.
Journal ArticleDOI
Congruent embodied representations for visually presented actions and linguistic phrases describing actions
Lisa Aziz-Zadeh,Lisa Aziz-Zadeh,Lisa Aziz-Zadeh,Stephen M. Wilson,Giacomo Rizzolatti,Marco Iacoboni +5 more
TL;DR: Results suggest a key role of mirror neuron areas in the re-enactment of sensory-motor representations during conceptual processing of actions invoked by linguistic stimuli.
Journal ArticleDOI
Three-dimensional locations and boundaries of motor and premotor cortices as defined by functional brain imaging: a meta-analysis.
TL;DR: The Human Motor Area Template (HMAT), a template that can be used for ROI analysis, was developed that characterized the shape, extent, and area of each sensorimotor region in 3-D.
References
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Journal ArticleDOI
A unified statistical approach for determining significant signals in images of cerebral activation.
TL;DR: A unified statistical theory for assessing the significance of apparent signal observed in noisy difference images is presented and an estimate of the P‐value for local maxima of Gaussian, t, χ2 and F fields over search regions of any shape or size in any number of dimensions is estimated.
Journal ArticleDOI
Assessing the significance of focal activations using their spatial extent
TL;DR: The results mean that detecting significant activations no longer depends on a fixed threshold, but can be effected at any (lower) threshold, in terms of the spatial extent of the activated region.
Journal ArticleDOI
Functional MRI evidence for adult motor cortex plasticity during motor skill learning
Avi Karni,G. Meyer,G. Meyer,Peter Jezzard,Michelle M. Adams,Robert Turner,Leslie G. Ungerleider +6 more
TL;DR: A slowly evolving, long-term, experience-dependent reorganization of the adult Ml is suggested, which may underlie the acquisition and retention of the motor skill.
Journal ArticleDOI
Upcrossings of Random Fields
TL;DR: In this article, the authors consider two point processes in R" whose properties are related to those of the maximum point process in R. The point processes are considered in particular two such processes: