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Journal ArticleDOI
Assessment of prognostic factors in alcoholic liver disease: toward a global quantitative expression of severity
TL;DR: The prognostic significance of a battery of clinical, laboratory, and histological indicators was assessed in relation to mortality risk in a 1‐year study of 253 patients with alcoholic liver disease, of whom 51 died within such time.
Journal ArticleDOI
Perioperative myocardial ischemia in patients undergoing noncardiac surgery—II: Incidence and severity during the 1st week after surgery☆
Dennis T. Mangano,Martin G. Wong,Martin G. Wong,Martin J. London,Martin J. London,Julio F. Tubau,Julio F. Tubau,Joseph A. Rapp,Joseph A. Rapp +8 more
TL;DR: Electrocardiographic changes consistent with ischemia were continuously monitored using ambulatory solid state ECG in 100 patients with or at risk for coronary artery disease and most ischemic episodes (57%) were associated with tachycardia.
Journal ArticleDOI
Predicting the likelihood of carrying a BRCA1 or BRCA2 mutation: validation of BOADICEA, BRCAPRO, IBIS, Myriad and the Manchester scoring system using data from UK genetics clinics.
Antonis C. Antoniou,Rachel Hardy,Leslie G. Walker,D G R Evans,A Shenton,Rosalind A. Eeles,Susan Shanley,Gabriella Pichert,Louise Izatt,S. Rose,Fiona Douglas,Diana Eccles,Patrick J. Morrison,J. Scott,R.L. Zimmern,Douglas F. Easton,Pharoah Pd +16 more
TL;DR: Carrier prediction algorithms provide a rational basis for counselling individuals likely to carry BRCA1 or BRCa2 mutations and their widespread use would improve equity of access and the cost-effectiveness of genetic testing.
Journal ArticleDOI
Plasma apolipoprotein B and VLDL-, LDL-, and HDL-cholesterol as risk factors in the development of coronary artery disease in male patients examined by angiography.
Thomas F. Whayne,Petar Alaupovic,Michael D. Curry,Elisa T. Lee,Paul S. Anderson,Eliot Schechter +5 more
TL;DR: Results of this study indicate that measurement of ApoB may offer important predictive value for coronary artery disease, especially at lower levels of plasma cholesterol.
Journal ArticleDOI
N-Myc gene amplification is a major prognostic factor in localized neuroblastoma: results of the French NBL 90 study. Neuroblastoma Study Group of the Société Francaise d'Oncologie Pédiatrique.
Hervé Rubie,Olivier Hartmann,Jean Michon,D. Frappaz,Carole Coze,Pascal Chastagner,M. C. Baranzelli,Dominique Plantaz,Hervé Avet-Loiseau,Jean Bénard,Olivier Delattre,M. Favrot,M C Peyroulet,Antoine Thyss,Yves Perel,Christophe Bergeron,B Courbon-Collet,J P Vannier,Jean Lemerle,Danièle Sommelet +19 more
TL;DR: The data confirm the overall good prognosis of localized NBs, even when unresectable, and NMA is the most relevant adverse prognostic factor in localized NB, and more intensive treatment should be investigated in these patients.