Open AccessJournal Article
The anticardiolipin syndrome
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This article is published in The Journal of Rheumatology.The article was published on 1986-06-01 and is currently open access. It has received 998 citations till now.read more
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Journal ArticleDOI
The antiphospholipid syndrome.
TL;DR: The broad spectrum of renal diseases that have been observed in association with this syndrome are discussed, and the impact that APS may have on pre-existing renal disease as well as current recommendations for treatment of APS are discussed.
Journal ArticleDOI
Anticardiolipin antibodies recognize beta 2-glycoprotein I structure altered by interacting with an oxygen modified solid phase surface.
TL;DR: Anticardiolipin antibodies derived from the sera of individuals exhibiting the antiphospholipid syndrome directly bind to beta 2- glycoprotein I (beta 2-GPI), which is adsorbed to an oxidized polystyrene surface by irradiation with electron or gamma-ray radiation.
Journal ArticleDOI
Catastrophic antiphospholipid syndrome. Clinical and laboratory features of 50 patients.
Ronald A. Asherson,Ricard Cervera,Jean-Charles Piette,Josep Font,J. T. Lie,Arsinur Burcoglu,Ken Lim,Francisco J. Muñoz-Rodríguez,Roger A. Levy,François Boué,Jérôme Rossert,Miguel Ingelmo +11 more
TL;DR: The majority of patients manifested microangiopathy--that is, occlusive vascular disease affecting predominantly small vessels of organs, particularly kidney, lungs, brain, heart, and liver--with a minority of patients experiencing only large vessel occlusions.
Book ChapterDOI
Immunology and clinical importance of antiphospholipid antibodies.
TL;DR: It is not generally recommended that this treatment be offered to individuals in whom aPL antibodies are detected but who have not suffered previous thromboses, since the risk of such events does not appear to be equal within a group of aPL antibody-positive persons.