The chemical constituents and diverse pharmacological importance of Tinospora cordifolia
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TLDR
The present review highlights the pharmacological importance of Tinospora cordifolia viz antioxidant activity, antimicrobial activity, antibacterial activity, antifungal activity, anti-diabetic activity, anticancer anti HIV potential, antiosteoporotic effects, antitoxic effects, wound healing, anticomplementary activity, and immunomodulating activity, systemic infection and Parkinson's disease.About:
This article is published in Heliyon.The article was published on 2019-09-01 and is currently open access. It has received 122 citations till now. The article focuses on the topics: Tinospora cordifolia.read more
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Targeting COVID-19 (SARS-CoV-2) main protease through active phytochemicals of ayurvedic medicinal plants - Withania somnifera (Ashwagandha), Tinospora cordifolia (Giloy) and Ocimum sanctum (Tulsi) - a molecular docking study.
Priya Shree,Priyanka Mishra,Chandrabose Selvaraj,Sanjeev Kumar Singh,Radha Chaube,Neha Garg,Yamini B. Tripathi +6 more
TL;DR: It could be suggested that active phytochemicals from medicinal plants could potentially inhibit Mpro of SARS-CoV-2 and further equip the management strategy against COVID-19-a global contagion.
Journal ArticleDOI
Bioactive Compounds in Anti-Diabetic Plants: From Herbal Medicine to Modern Drug Discovery
Ngan Tran,Bao Pham,Ly Le +2 more
TL;DR: Traditional medicine performed a good clinical practice and is showing a bright future in the therapy of diabetes mellitus, and some new bioactive drugs isolated from plants showed antidiabetic activity with more efficacy than oral hypoglycemic agents used in clinical therapy.
Journal ArticleDOI
In silico investigation of phytoconstituents from Indian medicinal herb ' Tinospora cordifolia (giloy)' against SARS-CoV-2 (COVID-19) by molecular dynamics approach.
TL;DR: The recent appearance of COVID-19 virus has created a global crisis due to unavailability of any vaccine or drug that can effectively and deterministically work against it as mentioned in this paper.
Journal ArticleDOI
Screening of phytochemical compounds of Tinospora cordifolia for their inhibitory activity on SARS-CoV-2: an in silico study.
S. Krupanidhi,K. Abraham Peele,T.C. Venkateswarulu,Vijaya Sai Ayyagari,Nazneen Bobby,D. John Babu,A Venkata Narayana,G Aishwarya +7 more
TL;DR: It was confirmed that tinosponone is the potent inhibitor of main protease of SARS-CoV-2 with the best binding affinity of −7.7 kcal/mol and ADME along with toxicity analysis was studied to predict the pharmacokinetics and drug-likeness properties of five top hits compounds.
Journal ArticleDOI
Phytochemistry and pharmacological activity of the genus artemisia.
TL;DR: Artemisia and its allied species have been employed for conventional medicine in the Northern temperate regions of North America, Europe, and Asia for the treatments of digestive problems, morning sickness, irregular menstrual cycle, typhoid, epilepsy, renal problems, bronchitis malaria, etc as discussed by the authors.
References
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Journal ArticleDOI
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma.
TL;DR: The human paracaspase prodomain binds Bcl10, a protein involved in the t(1;14)(p22;q32) translocation of mucosa-associated lymphoid tissue (MALT) lymphoma, and it is found that this fusion activates NF-kappaB and that the caspase domain is required for this function, since mutation of the conserved catalytic cysteine attenuates NF- kappaB activation.
Journal Article
Identification of paracaspases and metacaspases: two ancient families of caspase-like proteins, one of which plays a key role in MALT lymphoma
Journal ArticleDOI
Curcumin: A review of anti-cancer properties and therapeutic activity in head and neck squamous cell carcinoma
Reason Wilken,Mysore S. Veena,Mysore S. Veena,Marilene B. Wang,Marilene B. Wang,Eri S. Srivatsan,Eri S. Srivatsan +6 more
TL;DR: An overview of the current in vitro and in vivo data supporting its therapeutic activity in head and neck cancer as well as some of the challenges concerning its development as an adjuvant chemotherapeutic agent are presented.
Journal Article
Chemistry and medicinal properties of tinospora cordifolia (GUDUCHI)
TL;DR: A detailed survey of the literature on chemistry and medicinal properties of Tinospora cordifolia is presented in this paper, where the notable medicinal properties reported are anti-diabetic, anti-periodic and anti-spasmodic.
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MicroRNA-148b is frequently down-regulated in gastric cancer and acts as a tumor suppressor by inhibiting cell proliferation
Yongxi Song,Zhenyu Yue,Zhenning Wang,Ying-Ying Xu,Yang Luo,Huimian Xu,Xue Zhang,Li Jiang,Chengzhong Xing,Yong Zhang +9 more
TL;DR: It is found that miR-148b could inhibit cell proliferation in vitro by MTT assay, growth curves and an anchorage-independent growth assay in MGC-803, SGC-7901, BGC-823 and AGS cells, and an experiment in nude mice revealed that miCKBR could suppress tumorigenicity in vivo.