Journal ArticleDOI
The correlation of near-infrared spectroscopy with changes in oxygen delivery in a controlled model of altered perfusion.
Brant Putnam,Scott Bricker,Peter Fedorka,Juliette Zelada,Saad Shebrain,Bassam Omari,Frederic Bongard +6 more
TLDR
Compared with standard hemodynamic and biochemical variables in 40 patients undergoing cardiopulmonary bypass, StO2 is a reliable, noninvasive monitor of perfusion, which correlates well with oxygen delivery and identifies perfusion deficits earlier than lactate or base deficit.Abstract:
Alterations in regional tissue perfusion may precede global indications of shock. This study compared regional tissue oxygenation saturation (StO2) using near-infrared spectroscopy with standard he...read more
Citations
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Journal ArticleDOI
Monitoring tissue oxygenation by near infrared spectroscopy (NIRS): background and current applications
TL;DR: It is shown that tissue hypoxia occurs frequently in the perioperative setting, particularly in cardiac surgery, and measuring and obtaining adequate tissue oxygenation may prevent (postoperative) complications and may thus be cost-effective.
Journal ArticleDOI
Cerebral and tissue oximetry
Jochen Steppan,Charles W. Hogue +1 more
TL;DR: Wide, routine use of NIRS as a standard-of-care monitor cannot be recommended at present, but a novel application of processed NirS information for monitoring cerebral autoregulation and tissue oxygenation is promising.
Journal ArticleDOI
Tissue oxygen saturation predicts the need for early blood transfusion in trauma patients.
TL;DR: The need for blood transfusion within 24 hours of arrival was not predicted by hypotension, tachycardia, arterial lactate, base deficit, or hemoglobin, and StO2 may represent an important screening tool for identifying trauma patients who require blood transfusions or other limited medical resources.
Journal ArticleDOI
Differential effects of phenylephrine and norepinephrine on peripheral tissue oxygenation during general anaesthesia: A randomised controlled trial.
Marieke Poterman,Jaap Jan Vos,Hugo Vereecke,Michel Struys,Henk Vanoverschelde,Thomas Scheeren,Alain Kalmar +6 more
TL;DR: In normovolaemic patients under balanced propofol/remifentanil anaesthesia, phenylephrine and norepinephrine produced similar clinical effects when used to counteract anaesthesia-induced hypotension.
Journal ArticleDOI
Tissue Oxygen Saturation and Outcome after Cardiac Surgery
TL;DR: In patients undergoing cardiac surgery, reduced tissue oxygen saturation in the thenar eminence may be associated with poor postoperative outcome and measures to improve the balance between oxygen delivery and consumption might improve both tissue oxygenaturation and outcome.
References
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Journal ArticleDOI
Validation of near-infrared spectroscopy in humans.
TL;DR: 760-800 nm absorption is closely correlated with venous oxygen saturation, minimally affected by skin blood flow, altered by changes in limb perfusion, and primarily derived from deoxygenated hemoglobin and not myoglobin.
Journal ArticleDOI
Lactate Clearance and Survival Following Injury
David Abramson,Thomas M. Scalea,Robyn Hitchcock,Stanley Z. Trooskin,Sharon Henry,Joshua Greenspan +5 more
TL;DR: Evaluating 76 consecutive patients with multiple trauma admitted directly to the ICU from the operating room or emergency department found the time needed to normalize serum lactate levels is an important prognostic factor for survival in severely injured patients.
Journal ArticleDOI
Performance of near-infrared spectroscopy in measuring local O(2) consumption and blood flow in skeletal muscle.
TL;DR: NIRS is an appropriate tool to provide information about local muscV(O(2)) and local FBF because both place and depth of the NIRS measurements reveal local differences that are not detectable by the more established, but also more global, Fick method.
Journal ArticleDOI
Early predictors of postinjury multiple organ failure.
Angela Sauaia,Frederick A. Moore,Ernest E. Moore,James B. Haenel,Robert A. Read,Dennis C. Lezotte +5 more
TL;DR: Age greater than 55 years, ISS greater than or equal to 25, and greater than 6 U RBC/12 hours are early independent predictors of MOF.
Journal ArticleDOI
The golden hour and the silver day: detection and correction of occult hypoperfusion within 24 hours improves outcome from major trauma.
TL;DR: Early identification and aggressive resuscitation aimed at correcting continued elevation in serum lactate improves survival and reduces complications in severely injured trauma patients and persistent OH is associated with higher rates of RC, MSOF, and death after severe trauma.
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