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Open AccessJournal ArticleDOI

Cerebral and tissue oximetry

TLDR
Wide, routine use of NIRS as a standard-of-care monitor cannot be recommended at present, but a novel application of processed NirS information for monitoring cerebral autoregulation and tissue oxygenation is promising.
About
This article is published in Best Practice & Research Clinical Anaesthesiology.The article was published on 2014-12-01 and is currently open access. It has received 96 citations till now. The article focuses on the topics: Cerebral oxygen saturation.

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Citations
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Cerebral Autoregulation-oriented Therapy at the Bedside: A Comprehensive Review

TL;DR: The evidence indicates that monitoring of continuous cerebral autoregulation at the bedside is feasible and has the potential to be used to direct blood pressure management in acutely ill patients.
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Near-Infrared Spectroscopy in Adult Cardiac Surgery Patients: A Systematic Review and Meta-Analysis

TL;DR: It is established that reference values for baseline NIRS-derived SctO2 in cardiac surgery patients are varied and interventions that modulate SCTO2 are identified, which opens the door to standardized research and interventional studies in this field.
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Cerebral oximetry and its role in adult cardiac, non-cardiac surgery and resuscitation from cardiac arrest

TL;DR: A narrative review of monitors using near‐infra red spectroscopy to assess cerebral oxygenation levels non‐invasively in discrete areas of the brain aims to explore the rationale for using this technology but also the factors which have restricted its more widespread use.
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Cerebral Blood Flow Autoregulation in Sepsis for the Intensivist Why Its Monitoring May Be the Future of Individualized Care

TL;DR: Data reveal that individual BP goals determined from CBF autoregulation monitoring are more variable than previously expected, which suggests that the present consensus guidelines for BP management in sepsis may expose some patients to both cerebral hypoperfusion and cerebral hyperperfusion, potentially resulting in damage to brain parenchyma.
References
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Journal ArticleDOI

Beneficial effect of carotid endarterectomy in symptomatic patients with high-grade carotid stenosis

TL;DR: Carotid endarterectomy is highly beneficial to patients with recent hemispheric and retinal transient ischemic attacks or nondisabling strokes and ipsilateral high-grade stenosis of the internal carotid artery.
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Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters

TL;DR: Observations by infrared transillumination in the exposed heart and in the brain in cephalo without surgical intervention show that oxygen sufficiency for cytochrome a,a3, function, changes in tissue blood volume, and the average hemoglobin-oxyhemoglobin equilibrium can be recorded effectively and in continuous fashion for research and clinical purposes.
Journal Article

Randomised trial of endarterectomy for recently symptomatic carotid stenosis: final results of the MRC European carotid surgery trial (ECST)

TL;DR: Carotid endarterectomy is indicated for most patients with a recent non-disabling carotid-territory ischaemic event when the symptomatic stenosis is greater than about 80%, but age and sex should also be taken into account in decisions on whether to operate.
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A review of the optical properties of biological tissues

TL;DR: The known optical properties (absorption, scattering, total attenuation, effective attenuation and/or anisotropy coefficients) of various biological tissues at a variety of wavelengths are reviewed in this article.
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Analysis of pooled data from the randomised controlled trials of endarterectomy for symptomatic carotid stenosis.

TL;DR: Re-analysis of the trials with the same measurements and definitions yielded highly consistent results, indicating that surgery is of some benefit for patients with 50-69% symptomatic stenosis, and highly beneficial for those with 70% symptome stenosis or greater but without near-occlusion.
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