B
Bruce A. McKinley
Researcher at Houston Methodist Hospital
Publications - 84
Citations - 7976
Bruce A. McKinley is an academic researcher from Houston Methodist Hospital. The author has contributed to research in topics: Resuscitation & Abdominal compartment syndrome. The author has an hindex of 43, co-authored 84 publications receiving 7496 citations. Previous affiliations of Bruce A. McKinley include Cornell University & Harvard University.
Papers
More filters
Journal ArticleDOI
A genomic storm in critically injured humans
Wenzhong Xiao,Wenzhong Xiao,Michael N. Mindrinos,Junhee Seok,Joseph Cuschieri,Alex G. Cuenca,Hong Gao,Douglas L. Hayden,Laura Hennessy,Ernest E. Moore,Joseph P. Minei,Paul E. Bankey,Jeffrey L. Johnson,Jason L. Sperry,Avery B. Nathens,Timothy R. Billiar,Michael West,Bernard H. Brownstein,Philip H. Mason,Henry V. Baker,Celeste C. Finnerty,Marc G. Jeschke,M. Cecilia Lopez,Matthew B. Klein,Richard L. Gamelli,Nicole S. Gibran,Brett D. Arnoldo,Weihong Xu,Yuping Zhang,Steven E. Calvano,Grace P. McDonald-Smith,David A. Schoenfeld,John D. Storey,J. Perren Cobb,H. Shaw Warren,Lyle L. Moldawer,David N. Herndon,Stephen F. Lowry,Ronald V. Maier,Ronald W. Davis,Ronald G. Tompkins,W. Xiao,M. Mindrinos,J. Seok,J. Cuschieri,R. Tompkins,Roger J. Davis,R. Maier,L. Moldawer,L. Hennessy,E. Moore,J. Minei,P. Bankey,J. Johnson,J. Sperry,A. Nathens,T. Billiar,M. West,B. Brownstein,D. Herndon,H. Baker,C. Finnerty,M. Jeschke,M. Lopez,M. Klein,R. Gamelli,N. Gibran,B. Arnoldo,G. McDonald-Smith,D. Schoenfeld,J. P. Cobb,Shaw Warren,A. Cuenca,S. Lowry,S. Calvano,Doug Hayden,P. Mason,H. Gao,J. Storey,Lily L. Altstein,Ulysses J. Balis,David G. Camp,K. De Asit,Brian G. Harbrecht,Shari Honari,Bruce A. McKinley,Carol L. Miller-Graziano,Frederick A. Moore,Grant E. O'Keefe,Laurence G. Rahme,Daniel G. Remick,Michael B. Shapiro,Richard D. Smith,Robert Tibshirani,Mehmet Toner,Bram Wispelwey,Wing Hung Wong +96 more
TL;DR: It is shown that critical injury in humans induces a genomic storm with simultaneous changes in expression of innate and adaptive immunity genes that alter the status of these genes in the immune system.
Journal ArticleDOI
Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care.
Lori F. Gentile,Alex G. Cuenca,Philip A. Efron,Darwin Ang,Azra Bihorac,Bruce A. McKinley,Lyle L. Moldawer,Frederick A. Moore +7 more
TL;DR: It is proposed that PICS is the dominant pathophysiology and phenotype that has replaced late MOF and prolongs surgical ICU stay, usually with poor outcome.
Journal ArticleDOI
Fresh frozen plasma should be given earlier to patients requiring massive transfusion
Ernest A. Gonzalez,Frederick A. Moore,Frederick A. Moore,John B. Holcomb,Charles C. Miller,Rosemary A. Kozar,S. Rob Todd,S. Rob Todd,Christine S. Cocanour,Bjorn C Balldin,Bruce A. McKinley,Bruce A. McKinley +11 more
TL;DR: These data indicate acidosis and hypothermia to be well managed and suggest more aggressive pre-ICU intervention to correct coagulopathy may be effective in decreasing PRBC requirement during ICU resuscitation, and could improve outcome.
Journal ArticleDOI
Supranormal trauma resuscitation causes more cases of abdominal compartment syndrome.
Zsolt J. Balogh,Bruce A. McKinley,Christine S. Cocanour,Rosemary A. Kozar,Alicia Valdivia,R. Matthew Sailors,Frederick A. Moore +6 more
TL;DR: Supranormal resuscitation was associated with more lactated Ringer infusion, decreased intestinal perfusion (higher GAPCO2), and an increased incidence of IAH, ACS, multiple organ failure, and death.
Journal ArticleDOI
Both primary and secondary abdominal compartment syndrome can be predicted early and are harbingers of multiple organ failure.
Zsolt J. Balogh,Bruce A. McKinley,John B. Holcomb,Charles C. Miller,Christine S. Cocanour,Rosemary A. Kozar,Alicia Valdivia,Drue N. Ware,Frederick A. Moore +8 more
TL;DR: Primary and secondary ACS have similar demographics, injury severity, time to decompression from hospital admit, and bad outcome.