The current conceptualization of negative symptoms in schizophrenia.
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TLDR
The assessment of the negative symptom dimension has recently improved, but even current expert consensus‐based instruments diverge on several aspects and the use of objective measures might contribute to overcome uncertainties about the reliability of rating scales, but these measures require further investigation and validation.About:
This article is published in World Psychiatry.The article was published on 2017-02-01 and is currently open access. It has received 314 citations till now. The article focuses on the topics: Avolition & Asociality.read more
Citations
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Journal ArticleDOI
Negative symptoms of schizophrenia: new developments and unanswered research questions
TL;DR: If substantial progress is to be made in the understanding and treatment of negative symptoms, then advances in concepts and assessment should be integrated into the design of future studies of these symptoms.
Journal ArticleDOI
Negative Symptoms in Schizophrenia: A Review and Clinical Guide for Recognition, Assessment, and Treatment.
TL;DR: The objective of this review was to provide information that may be useful for clinicians treating patients with negative symptoms of schizophrenia, which constitute an unmet medical need in schizophrenia and new and effective treatments are urgently needed.
Journal ArticleDOI
Antipsychotic drugs for patients with schizophrenia and predominant or prominent negative symptoms: a systematic review and meta-analysis
Marc Krause,Marc Krause,Yikang Zhu,Yikang Zhu,Maximilian Huhn,Johannes Schneider-Thoma,Irene Bighelli,Adriani Nikolakopoulou,Stefan Leucht +8 more
TL;DR: Amisulpride is the only antipsychotic that outperformed placebo in the treatment of predominant negative symptoms, but there was a parallel reduction of depression.
Journal ArticleDOI
The Latent Structure of Negative Symptoms in Schizophrenia.
Gregory P. Strauss,Alicia Nuñez,Anthony O. Ahmed,Kimberly A. Barchard,Eric Granholm,Eric Granholm,Brian Kirkpatrick,James M. Gold,Daniel N. Allen +8 more
TL;DR: The findings suggest that the recent trend toward conceptualizing the latent structure of negative symptoms as 2 distinct dimensions does not adequately capture the complexity of the construct.
Journal ArticleDOI
The clinical characterization of the patient with primary psychosis aimed at personalization of management
Mario Maj,Jim van Os,Jim van Os,Jim van Os,Marc De Hert,Marc De Hert,Wolfgang Gaebel,Silvana Galderisi,Michael F. Green,Michael F. Green,Sinan Guloksuz,Sinan Guloksuz,Philip D. Harvey,Peter B. Jones,Dolores Malaspina,Patrick D. McGorry,Jouko Miettunen,Jouko Miettunen,Robin M. Murray,Keith H. Nuechterlein,Victor Peralta,Graham Thornicroft,Ruud van Winkel,Ruud van Winkel,Ruud van Winkel,Joseph Ventura +25 more
TL;DR: In this paper, the authors describe the salient domains that should be considered in the characterization of the individual patient with primary psychosis aimed at personalization of management, and provide simple assessment instruments that could be considered for use in clinical practice and included in standardized decision tools.
References
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Journal ArticleDOI
The Positive and Negative Syndrome Scale (PANSS) for Schizophrenia
TL;DR: Review of five studies involving the PANSS provided evidence of its criterion-related validity with antecedent, genealogical, and concurrent measures, its predictive validity, its drug sensitivity, and its utility for both typological and dimensional assessment.
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The Brief Psychiatric Rating Scale
John E. Overall,Donald R. Gorham +1 more
TL;DR: The Brief Psychiatric Rating Scale (BRS) as mentioned in this paper was developed to provide a rapid assessment technique particularly suited to the evaluation of patient change, and it is recommended for use where efficiency, speed, and economy are important considerations.
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Research domain criteria (RDoC): toward a new classification framework for research on mental disorders
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Dementia Praecox or the Group of Schizophrenias
TL;DR: It's coming again, the new collection that this site has; the favorite dementia praecox or the group of schizophrenias monograph series on schizophrenia no 1 book is offered today.
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Dementia praecox and paraphrenia
TL;DR: "Dementia Praecox and Paraphrenia" (1919) was the book in which Kraepelin first presented his work on schizophrenia to the English-speaking world, and it was probably the most influential psychiatric text of the entire 20th century, and has now become rare.