Journal ArticleDOI
The effect of ultra-violet light on the toxicity and the enzymatic and antigenic activities of snake venom
Panee Tejasen,Athos Ottolenghi +1 more
TLDR
A decrease in toxicity and inactivation of all three enzymes studied was clearly shown and no difference could be detected in the immunological response of rabbits to untreated and irradiated venom.About:
This article is published in Toxicon.The article was published on 1970-09-01. It has received 24 citations till now. The article focuses on the topics: Snake venom & Toxicity.read more
Citations
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Journal ArticleDOI
Immune Response Towards Snake Venoms
Guillermo León,Laura Sánchez,Andrés Hernández,Mauren Villalta,María Herrera,Álvaro Segura,Ricardo Estrada,José María Gutiérrez +7 more
TL;DR: The immune response to snake venoms, including those occurring in snakebite accidental envenomation, experimental vaccination and animal hyperimmunization for snake antivenom production are focused on.
Journal ArticleDOI
Influence of ionizing radiation on crotoxin: biochemical and immunological aspects.
TL;DR: The results indicate that irradiation of toxic proteins can promote significant detoxification, but still retain many of the original antigenic and immunological properties of native crotoxin.
Journal ArticleDOI
Irradiated Cerastes cerastes venom as a novel tool for immunotherapy.
TL;DR: Gamma irradiation effects on Cerastes cerastes venom showed that elicited antibodies to irradiated venoms were able to recognize native venom, and anti-2 kGy irradiated venom had more protective ability than anti-native venom, as tested in mice.
Journal ArticleDOI
Detoxification of snake venom using ionizing radiation
TL;DR: In this article, it is shown that when a compound is irradiated in a solution, the indirect effect joins the direct effect when the primary event, i.e., ionization, is produced in the molecule itself, and this indirect effect results from the reactions among the studied molecules and the products of radiation interaction with water or other solvents.
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Effects of 60Co gamma radiation on toxicity and hemorrhagic, myonecrotic, and edema-forming activities of Cerastes cerastes venom.
Hinda Abib,Fatima Laraba-Djebari +1 more
TL;DR: Results indicate that irradiation of venom with a 2-kGy dose may offer an effective method for reducing the chronic toxic effects of venom in immunized animals.
References
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A simplified method of evaluating dose-effect experiments.
J. T. Litchfield,F Wilcoxon +1 more
TL;DR: The method provides means for the rapid test of parallelism of two curves and easy computation of relative potency with its confidence limits and its accuracy is commensurate with the nature of dose-per cent effect data.
Journal Article
A simplified method of evaluating dose-effect experiments
J. T. Litchfield,F Wilcoxon +1 more
TL;DR: In this article, a rapid graphic method for approximating the median effective dose and the slope of dose-per-cent effect curves is presented, and confidence limits of both of these parameters for 19/20 probability are given by the method.
Journal ArticleDOI
A relation between non-esterified fatty acids in plasma and the metabolism of glucose
Journal ArticleDOI
Phospholipids. 4. On the composition of hen's egg phospholipids
D. N. Rhodes,C. H. Lea +1 more