Journal ArticleDOI
The Epidemiology of Chronic Hepatitis C and One-Time Hepatitis C Virus Testing of Persons Born During 1945 to 1965 in the United States
TLDR
This review highlights the epidemiology of hepatitis C and the importance of HCV testing and linkage to care in an era of more effective antiviral therapies.About:
This article is published in Clinics in Liver Disease.The article was published on 2013-02-01. It has received 63 citations till now. The article focuses on the topics: Hepatitis C & Hepatitis C virus.read more
Citations
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Journal ArticleDOI
Challenges of infectious diseases in the USA.
TL;DR: An important priority for control of infectious disease is to ensure that scientific and technological advances in molecular diagnostics and bioinformatics are well integrated into public health.
Journal ArticleDOI
Streamlining Screening to Treatment: The Hepatitis C Cascade of Care at Kaiser Permanente Mid-Atlantic States
M. Cabell Jonas,Carla V. Rodriguez,Jacquelyn L. Redd,Dana A Sloane,Bradley J. Winston,Bernadette Loftus +5 more
TL;DR: A comprehensive HCV screening pathway supported by a HCV care coordinator shows promise in closing gaps, including improving HCV RNA testing, communicating diagnoses, and assessing liver fibrosis and improved testing and linkage could increase curative treatment access.
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Implementation of a Large System-Wide Hepatitis C Virus Screening and Linkage to Care Program for Baby Boomers.
Mariana Castrejon,Kara W. Chew,Marjan Javanbakht,Romney M. Humphries,Sammy Saab,Jeffrey D. Klausner +5 more
TL;DR: Castrejon et al. as discussed by the authors implemented and evaluated a large health system-wide hepatitis C virus (HCV) screening and linkage to care program for persons born between 1945 and 1965 ("baby boomers").
Journal ArticleDOI
Health state utilities associated with attributes of treatments for hepatitis C
Louis S. Matza,Sandhya Sapra,John F. Dillon,A. Kalsekar,Evan W Davies,M.K. Devine,Jessica B Jordan,Amanda Landrian,David Feeny +8 more
TL;DR: Adverse events and greater treatment regimen complexity were associated with lower utility scores, suggesting a perceived decrease in quality of life beyond the impact of hepatitis C, which is used in models estimating and comparing the value of treatments for hepatitis C.
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Lack of health insurance limits the benefits of hepatitis C virus screening: insights from the National Health and Nutrition Examination Hepatitis C follow-up study.
Ivo Ditah,Badr F. Al Bawardy,Humberto C. Gonzalez,Behnam Saberi,Callistus Ditah,Patrick S. Kamath,Michael Charlton +6 more
TL;DR: This study suggests that the lack of health insurance may attenuate the theoretical benefits of a screening program that identifies asymptomatic HCV-infected individuals who are less likely to pursue downstream care.
References
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Journal ArticleDOI
Diagnosis, management, and treatment of hepatitis C: An update
TL;DR: This document has been approved by the AASLD, the Infectious Diseases Society of America, and the American College of Gastroenterology.
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Epidemiology of Viral Hepatitis and Hepatocellular Carcinoma
TL;DR: This review summarizes the risk factors for HCC among HBV- or HCV-infected individuals, based on findings from epidemiologic studies and meta-analyses, as well as determinants of patient outcome and the HCC disease burden, globally and in the United States.
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Telaprevir for Previously Untreated Chronic Hepatitis C Virus Infection
Ira M. Jacobson,John G. McHutchison,Geoffrey Dusheiko,Adrian M. Di Bisceglie,K. Rajender Reddy,Natalie Bzowej,Patrick Marcellin,Andrew J. Muir,Peter Ferenci,Robert Flisiak,Jacob George,Mario Rizzetto,Daniel Shouval,Ricard Sola,R. Terg,Eric M. Yoshida,Nathalie Adda,Leif Bengtsson,Abdul J. Sankoh,Tara L. Kieffer,Shelley George,Robert S. Kauffman,Stefan Zeuzem,Vertex Phar +23 more
TL;DR: Telaprevir with peginterferon-ribavirin was associated with significantly improved rates of sustained virologic response in patients with HCV genotype 1 infection who had not received previous treatment, with only 24 weeks of therapy administered in the majority of patients.
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Boceprevir for Untreated Chronic HCV Genotype 1 Infection
TL;DR: The addition of boceprevir to standard therapy with peginterferon–ribavirin, as com pared with standard therapy alone, significantly increased the rates of sustained virologic response in previously untreated adults with chronic HCV genotype 1 infection.
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The prevalence of hepatitis C virus infection in the United States, 1999 through 2002.
Gregory L. Armstrong,Annemarie Wasley,Edgar P. Simard,Geraldine M. McQuillan,Wendi L. Kuhnert,Miriam J. Alter +5 more
TL;DR: To determine the characteristics of HCV-infected persons in the general United States population today and to monitor trends in prevalence, data on HCV infection from the most recent NHANES was analyzed.