Journal ArticleDOI
The Mini Mental State Exam as a Predictor of Neuropsychological Functioning after Cardiac Surgery
Eileen J. Burker,James A. Blumenthal,Marc D. Feldman,Elizabeth Towner Thyrum,Elizabeth P. Mahanna,William D. White,L R Smith,Lewis Jb,Narda D. Croughwell,Randall M. Schell +9 more
TLDR
The results suggest that although the Mini Mental State Exam is widely used to assess cognitive mental status, it may have limited value in identifying patients with cognitive impairment post-cardiac surgery, and special attention must be paid to the cut-off scores used in interpreting the MMSE.Abstract:
Objective:The present longitudinal study was designed to: 1) determine the ability of the Mini Mental State Exam (MMSE) to predict neuropsychologic impairment based on neuropsychologic testing five to seven days and six weeks after cardiac surgery; and 2) to determine whether the traditional or the education-related MMSE norms are more appropriate to use for this purpose.Method:The day before surgery (T1), before hospital discharge (T2), and six weeks after surgery (T3), 247 subjects completed a battery of five neuropsychologic tests. Subjects also completed the Center for Epidemiological Studies Depression Scale and the Speilberger State-Trait Anxiety Inventory. Subjects completed the MMSE two to three days after surgery.Results:Stepwise regression analyses revealed that the MMSE significantly predicted only a small portion of the variance in neuropsychologic test performance at T2, and to an even lesser extent at T3, over and above the demographic variables. In assessing the association between an impai...read more
Citations
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Cerebral oxygen desaturation is associated with early postoperative neuropsychological dysfunction in patients undergoing cardiac surgery.
TL;DR: Intraoperative cerebral oxygen desaturation is associated with early postoperative neuropsychological dysfunction in patients undergoing elective cardiac surgery with cardiopulmonary bypass, and it remains to be determined whether interventions to maintain adequate cerebral oxygenation may improve Neuropsychological outcome.
Journal ArticleDOI
Neurocognitive outcome in brain metastases patients treated with accelerated-fractionation vs. accelerated-hyperfractionated radiotherapy: an analysis from Radiation Therapy Oncology Group Study 91-04.
TL;DR: Use of AH as compared to AF-WBRT was not associated with a significant difference in neurocognitive function as measured by MMSE in this patient population with unresectable brain metastases and limited survival, however, control ofbrain metastases had a significant impact on MMSE.
Journal ArticleDOI
Risk Factors for Delirium and Cognitive Decline Following Coronary Artery Bypass Grafting Surgery: A Systematic Review and Meta‐Analysis
Danielle Greaves,Peter J. Psaltis,Peter J. Psaltis,Daniel Davis,Tyler J. Ross,Erica S. Ghezzi,Amit Lampit,Amit Lampit,Ashleigh E. Smith,Hannah A.D. Keage +9 more
TL;DR: This meta‐analysis identified several key risk factors for delirium and cognitive decline following CABG, most of which are nonmodifiable.
Journal ArticleDOI
Key Papers in Geriatric Psychiatry: mini‐mental state: a practical method for grading the cognitive state of patients for the clinician. M. Folstein, S. Folstein and P. McHugh, Journal of Psychiatric Research, 1975, 12, 189‐198.
Journal ArticleDOI
Do blood levels of neuron-specific enolase and S-100 protein reflect cognitive dysfunction after coronary artery bypass?
TL;DR: It is hypothesised that blood levels of NSE and S‐100 protein would increase after coronary artery bypass surgery and that the change in blood level would correlate with thechange in cognitive function.
References
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Journal ArticleDOI
“Mini-mental state”: A practical method for grading the cognitive state of patients for the clinician
Marshal F. Folstein,Marshal F. Folstein,Susan E B Folstein,Susan E B Folstein,Paul R. McHugh,Paul R. McHugh +5 more
TL;DR: A simplified, scored form of the cognitive mental status examination, the “Mini-Mental State” (MMS) which includes eleven questions, requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
A practical method for grading the cognitive state of patients for the clinician
TL;DR: The Mini-Mental State (MMS) as mentioned in this paper is a simplified version of the standard WAIS with eleven questions and requires only 5-10 min to administer, and is therefore practical to use serially and routinely.
Journal ArticleDOI
The CES-D Scale: A Self-Report Depression Scale for Research in the General Population
TL;DR: The CES-D scale as discussed by the authors is a short self-report scale designed to measure depressive symptomatology in the general population, which has been used in household interview surveys and in psychiatric settings.
Journal ArticleDOI
Population-based norms for the mini-mental state examination by age and educational level
TL;DR: Results presented should prove to be useful to clinicians who wish to compare an individual patient's MMSE scores with a population reference group and to researchers making plans for new studies in which cognitive status is a variable of interest.
Journal ArticleDOI
The impact of microemboli during cardiopulmonary bypass on neuropsychological functioning
TL;DR: It is suggested that neuropsychological deficits after routine cardiopulmonary bypass are related to the number of microemboli delivered during surgery, and the numbers of microEmboli may be reduced by including a 40‐&mgr;m filter on the arterial line.