Journal ArticleDOI
The neuroleptic malignant syndrome: agent and host interaction.
Arieh Y. Shalev,Hanan Munitz +1 more
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This review comprises an exhaustive analysis of 120 case reports of neuroleptic malignant syndrome representing the majority of published clinical data on this syndrome, showing the rate of Neuroleptic loading to play a cardinal role in the development of NMS.Abstract:
This review comprises an exhaustive analysis of 120 case reports of neuroleptic malignant syndrome (NMS) representing the majority of published clinical data on this syndrome. Epidemiological, clinical and biological parameters, as well as those concerning the agent and the treatment of the syndrome, are critically evaluated on the basis of this data. The rate of neuroleptic loading is shown to play a cardinal role in the development of NMS. Rechallenge and aftercare of patients who need anti-psychotic treatment after NMS are considered.read more
Citations
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Journal ArticleDOI
Neuroleptic malignant syndrome
TL;DR: Data drawn from clinical observations and basic studies support the primary role of an acute reduction in brain dopamine activity in the development of neuroleptic malignant syndrome.
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Bath salts and synthetic cathinones: An emerging designer drug phenomenon
TL;DR: Insight is provided into the development of synthetic cathinones as substances of abuse, current patterns of their abuse, known mechanisms of their action and toxicology, and the benefits and drawbacks of their classification.
Book
Catatonia: A Clinician's Guide to Diagnosis and Treatment
Max Fink,Michael Alan Taylor +1 more
TL;DR: List of patient vignettes Preface Acknowledgments Chronology of catatonia concepts 1.
Journal ArticleDOI
A prospective analysis of 24 episodes of neuroleptic malignant syndrome.
TL;DR: Detailed data is presented concerning the clinical setting in which neuroleptic malignant syndrome occurs, the associated clinical and laboratory features, the favorable outcome that can be achieved with vigorous supportive therapy, and the factors that might help predict whether patients with neurolepsy will subsequently be able to tolerate the reintroduction of Neuroleptic medication.
Journal ArticleDOI
Neuroleptic Malignant Syndrome: Review and Analysis of 115 Cases
TL;DR: All case reports in the English-language literature for neuroleptic malignant syndrome for 43 variables are analyzed and the results are discussed in light of prior literature, and recommendations are made for future research.
References
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Journal Article
The neuroleptic malignant syndrome.
TL;DR: The clinical features of neuroleptic malignant syndrome are reviewed to enhance patient safety and reduce physician liability whenever antipsychotic drugs are administered.
Journal ArticleDOI
Comparative doses and costs of antipsychotic medication.
TL;DR: This article derives dosage comparability data by reviewing double-blind controlled studies that used a flexible dosage schedule of neuroleptics in treating schizophrenic patients by calculating the cost to provide such medication and constructing a table comparing the costs of the different neurolePTics.
Journal ArticleDOI
Neuroleptic malignant syndrome A pathogenetic role for dopamine receptor blockade
Victor W. Henderson,G. F. Wooten +1 more
TL;DR: In a patient with Parkinson disease and a chronic psychiatric disorder treated with haloperidol, typical features of NMS appeared upon cessation of dopaminergic antiparkinsonian drugs.
Book ChapterDOI
Neuroleptic Malignant Syndrome
TL;DR: Neuroleptic drugs are used extensively in the treatment of psychotic illnesses and are widely employed in general medicine as antiemetics, for dissociative anesthesia, and to treat diseases such as Tourette's syndrome.