The past and future of delusions research: from the inexplicable to the treatable.
Philippa Garety,Daniel Freeman +1 more
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TLDR
Theoretical work rendering delusions understandable can be translated into treatment; future clinical trials should focus on individual psychotic experiences as outcomes.Abstract:
Background
Problems with the diagnosis and treatment of schizophrenia have led for a call to change strategy and focus on individual psychotic experiences. In recent years, research on delusions has led the way.
Aims
To update our 1999 review of almost 40 studies on delusions.
Method
A systematic literature search was conducted of reasoning and affective processes related to delusions.
Results
Over 200 studies were identified. The presence of ‘jumping to conclusions’ in individuals with delusions has been substantiated, the theory of mind account has not stood up to subsequent testing, and there is a promising new focus on the ways that affective processes contribute to delusional experience.
Conclusions
Theoretical work rendering delusions understandable can be translated into treatment; future clinical trials should focus on individual psychotic experiences as outcomes.read more
Citations
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Journal ArticleDOI
Advances in understanding and treating persecutory delusions: a review
Daniel Freeman,Philippa Garety +1 more
TL;DR: The aim of the review is to provide an introduction to the understanding of persecutory delusions, highlight key putative causal factors that have the potential to be translated into efficacious treatment, and indicate future research directions.
The British journal of psychiatry
TL;DR: Papers Treatment of severe psychiatric illness in a day hospital, and the question of therapists' differential effectiveness: a Sheffield psychotherapy project addendum.
Journal ArticleDOI
Sowing the seeds of doubt: a narrative review on metacognitive training in schizophrenia.
Steffen Moritz,Christina Andreou,Brooke C. Schneider,Charlotte E. Wittekind,Mahesh Menon,Ryan P. Balzan,Todd S. Woodward +6 more
TL;DR: It is concluded that MCT appears to be a worthwhile complement to pharmacotherapy, as the preliminary data suggest that the individual MCT format is especially effective in addressing symptoms, cognitive biases and insight.
Journal ArticleDOI
Psychosis, Delusions and the “Jumping to Conclusions” Reasoning Bias: A Systematic Review and Meta-analysis
TL;DR: The JTC bias was linked to a greater probability of delusion occurrence in psychosis and nonaffective psychosis is characterized by a hasty decision-making style, which is linked to an increased probability of delusions.
Journal ArticleDOI
Acceptance and Efficacy of Metacognitive Training (MCT) on Positive Symptoms and Delusions in Patients With Schizophrenia: A Meta-analysis Taking Into Account Important Moderators
Carolin Eichner,Fabrice Berna +1 more
TL;DR: This meta-analysis demonstrates that MCT exerts a small to moderate effect on delusions and positive symptoms and a large effect on acceptance of the intervention.
References
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Journal ArticleDOI
The Dopamine Hypothesis of Schizophrenia: Version III—The Final Common Pathway
Oliver D. Howes,Shitij Kapur +1 more
TL;DR: The dopamine hypothesis of schizophrenia-version III is synthesized into a comprehensive framework that links risk factors, including pregnancy and obstetric complications, stress and trauma, drug use, and genes, to increased presynaptic striatal dopaminergic function.
Book
The Cognitive Neuropsychology of Schizophrenia
TL;DR: The Nature of Sch schizophrenia, Behavioural Abnormalities in Schizophrenia, and Communication in Sch schizophrenia: Linking the Mind and the Brain are studied.
Journal ArticleDOI
The attributional Style Questionnaire
Christopher Peterson,Amy Semmel,Carl L. von Baeyer,Lyn Y. Abramson,Gerald I. Metalsky,Martin E. P. Seligman +5 more
TL;DR: The Attributional Style Questionnaire as mentioned in this paper measures individual differences in the use of these attributional dimensions, and is used to measure individual differences between depressive symptoms and the learned helplessness model.
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An experimental investigation
Journal ArticleDOI
A cognitive model of the positive symptoms of psychosis.
TL;DR: The cognitive processes that are thought to lead to the formation and maintenance of the positive symptoms of psychosis are set out and a fuller integration with the findings of biological research will be required.