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Open AccessJournal ArticleDOI

The pineal gland: a pacemaker within the circadian system of the house sparrow.

Natille Headrick Zimmerman, +1 more
- 01 Feb 1979 - 
- Vol. 76, Iss: 2, pp 999-1003
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TLDR
Long-term recordings demonstrate a remarkable similarity between the circadian system in normal birds and that in birds bearing pineal transplants.
Abstract
Transplantation of pineal tissue into the anterior chamber of the eye rapidly reestablishes rhythmicity in arhythmic pinealectomized sparrows and also transfers the phase of the donor bird's rhythm to the host. Thus, the transplanted pineal does not merely permit rhythmicity to be expressed but rather transfers an oscillation that controls the remainder of the circadian system and restores the capacity for self-sustained rhythmicity. Long-term recordings, during which sparrosw were exposed to various lighting conditions, demonstrate a remarkable similarity between the circadian system in normal birds and that in birds bearing pineal transplants.

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Transplanted suprachiasmatic nucleus determines circadian period

TL;DR: The pacemaker role of the suprachiasmatic nucleus in a mammalian circadian system was tested by neural transplantation by using a mutant strain of hamster that shows a short circadian period to restore circadian rhythms to arrhythmic animals whose own nucleus had been ablated.
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Circadian rhythms from multiple oscillators: lessons from diverse organisms

TL;DR: Comparisons of circadian clocks in unicellular and multicellular organisms using molecular genetics and genomics have provided new insights into the mechanisms and complexity of clock systems.
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Persistence of circadian rhythmicity in a mammalian hypothalamic "island" containing the suprachiasmatic nucleus

TL;DR: Simultaneous recording from two extracellular electrodes indicated neural activity at two sites in the brain, one of which is in or near the suprachiasmatic nucleus and the other in one of many other brain locations, which indicated clear circadian rhythmicity of spontaneous neural activity.
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Photoperiodic Control of Seasonality in Birds

TL;DR: This review examines how birds use the annual cycle in photoperiod to ensure that seasonal events—breeding, molt, and song production—happen at the appropriate time of year.
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Cellular Mechanisms of Melatonin Action

TL;DR: Molecular mechanisms of the melatonin effects are not clear but may involve at least two parallel transduction pathways, one inhibiting adenylyl cyclase and the other regulating phospholipide metabolism and [Ca2+]i.
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