Journal ArticleDOI
The renal lesion in congenital chloride diarrhea
TLDR
Renal function and growth were reduced, and the hormonal activities were high, evidently due to chronic dehydration, and only the addition of NaCl corrected the hyperaldosteronism.About:
This article is published in The Journal of Pediatrics.The article was published on 1977-11-01. It has received 50 citations till now. The article focuses on the topics: Congenital chloride diarrhea & Hyperaldosteronism.read more
Citations
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Book ChapterDOI
Congenital chloride diarrhoea.
TL;DR: The only ions known to be involved in specific malabsorption states are Zn+ (Rahanzadeh and Danzig 1974), Cu2+ (Danks et al. 1972) and C1-. Malabsorption of C1- is known as congenital chloride diarrhea (CCD) as discussed by the authors.
Journal ArticleDOI
SLC26A3 mutations in congenital chloride diarrhea
TL;DR: A summary of all published and two novel SLC26A3 mutations and polymorphisms are presented, and they are reviewed in the context of their functional consequences and clinical implications.
Journal ArticleDOI
Congenital chloride diarrhoea. Clinical analysis of 21 Finnish patients.
TL;DR: The watery diarrhoea persists and increases slightly with age, though patients learn to live with their disease and to make an adequate social adjustment, and treatment prevents the renal lesions and the retarded growth and psychomotor development.
Congenital chloride diarrhea.
TL;DR: Specific disturbances of intestinal electrolyte transport are very rare, and the only ions known to be involved in specific malabsorption states are Zn+ (Rahanzadeh and Danzig 1974), Cu2+ (Danks et al. 1972) and C1-.
Journal ArticleDOI
Long-term clinical outcome in patients with congenital chloride diarrhea.
TL;DR: When early diagnosed and adequately treated, the long-term prognosis of CLD is favorable and a putative role of a primary anion exchange defect of SLC26A3 in male subfertility and the decline of renal function due to chronic dehydration deserve further characterization.
References
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Book
Textbook of endocrinology
TL;DR: To squeeze all of this into a man¬ ageable volume, the publisher has gone to a smaller type size than before, smaller than usual in medical texts, but the end result is a uniform, informative style.
Journal ArticleDOI
Serum creatinine determination without protein precipitation
H. Bartels,M. Böhmer,C. Heierli +2 more
TL;DR: A simple method for the determination of creatinine at a picric acid concentration of 5.7 mmoles/l with high specificity is described, and the colour produced during the reaction can be estimated at 492 nm.
Journal ArticleDOI
Radioimmunoassay of plasma renin activity.
TL;DR: A sensitive, simplified radioimmunoassay method for determination of plasma renin activity, using a single addition of hydrochloric acid and the enzyme inhibitor hydroxyquinoline, indicating satisfactory protection from proteolytic enzymes.
Journal ArticleDOI
Congenital alkalosis with diarrhea
TL;DR: Metabolic data are presented which show that as chloride is lost more rapidly than sodium, extracellular sodium is transferred into intracellular fluids and approximately equivalent amounts of potassium are released from the cells and excreted.
Journal ArticleDOI
Cardiovascular-disease mortality trends and oral-contraceptive use in young women.
TL;DR: Findings suggest that the range of vascular diseases affected by oral-contraceptive use and the size of the associated risks may be greater than previously recognised and may exist not only with the pills containing high oestrogen doses, but also with the new "lower dose" pills.